| Reaction Details |
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 | Report a problem with these data |
| Target | Zinc finger protein GLI1 |
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| Ligand | BDBM89373 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response confirmation of uHTS antagonist hits from Gli-SUFU in a luminescent reporter assay |
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| IC50 | 1020±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation of uHTS antagonist hits from Gli-SUFU in a luminescent reporter assay PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Zinc finger protein GLI1 |
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| Name: | Zinc finger protein GLI1 |
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| Synonyms: | GLI1_MOUSE | Gli | Gli1 | Glioma-associated oncogene homolog |
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| Type: | PROTEIN |
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| Mol. Mass.: | 118579.34 |
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| Organism: | Mus musculus |
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| Description: | EBI_101259 |
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| Residue: | 1111 |
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| Sequence: | MFNPMTPPQVNSYSEPCCLRPLHSQGVPSMGTEGLSGLPFCHQANFMSGSQGYGAARETS
SCTEGSLFPPPPPPRSSVKLTKKRALSISPLSDASLDLQTVIRTSPSSLVAFINSRCTSP
GGSYGHLSIGTMSPSLGFPPQMSHQKGTSPPYGVQPCVPHDSTRGSMMLHPQSRGPRATC
QLKSELDMMVGKCPEDPLEGDMSSPNSTGTQDHLLGMLDGREDLEREEKPEPESVYETDC
RWDGCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTG
EKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEQEGCSKAFSNASDRAKHQNRTHS
NEKPYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDGPLPRAQPLSTVEPKRE
REGGSGREESRLTVPESAMPQQSPGAQSSCSSDHSPAGSAANTDSGVEMAGNAGGSTEDL
SSLDEGPCVSATGLSTLRRLENLRLDQLHQLRPIGSRGLKLPSLTHAGAPVSRRLGPPVS
LDRRSSSSSSMSSAYTVSRRSSLASPFPPGTPPENGASSLPGLTPAQHYMLRARYASARG
SGTPPTAAHSLDRMGGLSVPPWRSRTEYPGYNPNAGVTRRASDPARAADHPAPARVQRFK
SLGCVHTPPSVATGRNFDPHHPTSVYSPQPPSITENVAMDTRGLQEEPEVGTSVMGNGLN
PYMDFSSTDTLGYGGPEGTAAEPYEARGPGSLPLGPGPPTNYGPGHCAQQVSYPDPTPEN
WGEFPSHAGVYPSNKAPGAAYSQCPRLEHYGQVQVKPEQGCPVGSDSTGLAPCLNAHPSE
GSPGPQPLFSHHPQLPQPQYPQSGPYPQPPHGYLSTEPRLGLNFNPSSSHSTGQLKAQLV
CNYVQSQQELLWEGRNRGGLPNQELPYQSPKFLGGSQVSQSPAKTPAAAAAAYGSGFAPA
SANHKSGSYPAPSPCHETFTVGVNRPSHRPAAPPRLLPPLSPCYGPLKVGDTNPSCGHPE
VGRLGAGPALYPPPEGQVCNALDSLDLDNTQLDFVAILDEAQGLSPPLSHEQGDSSKNTP
SPSGPPNMAVGNMSVLLGSLPGETQFLNSSA
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| BDBM89373 |
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| n/a |
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| Name | BDBM89373 |
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| Synonyms: | 1-[4-(4-bromophenyl)-1,3-thiazol-2-yl]azepane | 2-(1-azepanyl)-4-(4-bromophenyl)thiazole | 2-(azepan-1-yl)-4-(4-bromophenyl)-1,3-thiazole | 2-(azepan-1-yl)-4-(4-bromophenyl)thiazole | MLS001178940 | SMR000477383 | cid_838339 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H17BrN2S |
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| Mol. Mass. | 337.278 |
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| SMILES | Brc1ccc(cc1)-c1csc(n1)N1CCCCCC1 |
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| Structure | 
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