Reaction Details |
| Report a problem with these data |
Target | Corticotropin-releasing factor-binding protein |
---|
Ligand | BDBM44436 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex |
---|
EC50 | 5230±n/a nM |
---|
Citation | PubChem, PC Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex PubChem Bioassay(2012)[AID] |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Corticotropin-releasing factor-binding protein |
---|
Name: | Corticotropin-releasing factor-binding protein |
Synonyms: | CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 36143.95 |
Organism: | Homo sapiens (Human) |
Description: | P24387 |
Residue: | 322 |
Sequence: | MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRC
LDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKG
EKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNL
FPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGI
GDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQ
LEPYELENPNGNSIGEFCLSGL
|
|
|
BDBM44436 |
---|
n/a |
---|
Name | BDBM44436 |
Synonyms: | 3-phenyl-1-propyl-pyrazolo[4,3-b]quinoxaline | 3-phenyl-1-propylpyrazolo[4,3-b]quinoxaline | MLS000040578 | SMR000045830 | cid_664831 |
Type | Small organic molecule |
Emp. Form. | C18H16N4 |
Mol. Mass. | 288.3464 |
SMILES | CCCn1nc(-c2ccccc2)c2nc3ccccc3nc12 |
Structure |
|