Reaction Details |
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Target | Corticotropin-releasing factor-binding protein |
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Ligand | BDBM42908 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex |
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EC50 | >53000±n/a nM |
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Citation | PubChem, PC Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex PubChem Bioassay(2012)[AID] |
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More Info.: | Get all data from this article, Assay Method |
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Corticotropin-releasing factor-binding protein |
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Name: | Corticotropin-releasing factor-binding protein |
Synonyms: | CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 36143.95 |
Organism: | Homo sapiens (Human) |
Description: | P24387 |
Residue: | 322 |
Sequence: | MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRC
LDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKG
EKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNL
FPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGI
GDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQ
LEPYELENPNGNSIGEFCLSGL
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BDBM42908 |
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n/a |
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Name | BDBM42908 |
Synonyms: | 6-(5-bromanylfuran-2-yl)-3-(4-chlorophenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole | 6-(5-bromo-2-furanyl)-3-(4-chlorophenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole | 6-(5-bromo-2-furyl)-3-(4-chlorophenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole | 6-(5-bromofuran-2-yl)-3-(4-chlorophenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole | MLS000041398 | SMR000046266 | cid_665202 |
Type | Small organic molecule |
Emp. Form. | C13H6BrClN4OS |
Mol. Mass. | 381.635 |
SMILES | Clc1ccc(cc1)-c1nnc2sc(nn12)-c1ccc(Br)o1 |
Structure |
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