| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Corticotropin-releasing factor-binding protein |
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| Ligand | BDBM44437 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex |
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| EC50 | 6660±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Corticotropin-releasing factor-binding protein |
|---|
| Name: | Corticotropin-releasing factor-binding protein |
|---|
| Synonyms: | CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36143.95 |
|---|
| Organism: | Homo sapiens (Human) |
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| Description: | P24387 |
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| Residue: | 322 |
|---|
| Sequence: | MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRC
LDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKG
EKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNL
FPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGI
GDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQ
LEPYELENPNGNSIGEFCLSGL
|
|
|
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| BDBM44437 |
|---|
| n/a |
|---|
| Name | BDBM44437 |
|---|
| Synonyms: | 1-ethyl-3-phenyl-pyrazolo[4,3-b]quinoxaline | 1-ethyl-3-phenylpyrazolo[4,3-b]quinoxaline | MLS000041625 | SMR000046273 | cid_665240 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H14N4 |
|---|
| Mol. Mass. | 274.3199 |
|---|
| SMILES | CCn1nc(-c2ccccc2)c2nc3ccccc3nc12 |
|---|
| Structure | 
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|---|
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