| Reaction Details |
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 | Report a problem with these data |
| Target | Corticotropin-releasing factor-binding protein |
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| Ligand | BDBM57053 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex |
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| EC50 | 8830±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Corticotropin-releasing factor-binding protein |
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| Name: | Corticotropin-releasing factor-binding protein |
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| Synonyms: | CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36143.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P24387 |
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| Residue: | 322 |
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| Sequence: | MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRC
LDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKG
EKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNL
FPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGI
GDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQ
LEPYELENPNGNSIGEFCLSGL
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| BDBM57053 |
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| n/a |
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| Name | BDBM57053 |
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| Synonyms: | MLS000068601 | N-(4-Bromo-phenyl)-2-(3-cyano-4-methyl-6-oxo-1,6-dihydro-pyridin-2-ylsulfanyl)-acetamide | N-(4-bromophenyl)-2-[(3-cyano-4-methyl-6-oxidanylidene-1H-pyridin-2-yl)sulfanyl]ethanamide | N-(4-bromophenyl)-2-[(3-cyano-4-methyl-6-oxo-1H-pyridin-2-yl)sulfanyl]acetamide | N-(4-bromophenyl)-2-[(3-cyano-4-methyl-6-oxo-1H-pyridin-2-yl)thio]acetamide | N-(4-bromophenyl)-2-[(3-cyano-6-keto-4-methyl-1H-pyridin-2-yl)thio]acetamide | SMR000122935 | cid_1069285 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H12BrN3O2S |
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| Mol. Mass. | 378.244 |
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| SMILES | Cc1cc(=O)[nH]c(SCC(=O)Nc2ccc(Br)cc2)c1C#N |
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| Structure | 
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