Reaction Details |
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Target | Corticotropin-releasing factor-binding protein |
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Ligand | BDBM90162 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex |
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EC50 | >53000±n/a nM |
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Citation | PubChem, PC Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex PubChem Bioassay(2012)[AID] |
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More Info.: | Get all data from this article, Assay Method |
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Corticotropin-releasing factor-binding protein |
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Name: | Corticotropin-releasing factor-binding protein |
Synonyms: | CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 36143.95 |
Organism: | Homo sapiens (Human) |
Description: | P24387 |
Residue: | 322 |
Sequence: | MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRC
LDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKG
EKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNL
FPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGI
GDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQ
LEPYELENPNGNSIGEFCLSGL
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BDBM90162 |
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n/a |
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Name | BDBM90162 |
Synonyms: | (2-fluorophenyl)methyl N-cyano-N'-(3-fluorophenyl)carbamimidothioate | 1-cyano-2-(2-fluorobenzyl)-3-(3-fluorophenyl)isothiourea | MLS000592109 | N-cyano-N'-(3-fluorophenyl)carbamimidothioic acid (2-fluorophenyl)methyl ester | SMR000218316 | cid_1947246 |
Type | Small organic molecule |
Emp. Form. | C15H11F2N3S |
Mol. Mass. | 303.33 |
SMILES | Fc1cccc(c1)N=C(NC#N)SCc1ccccc1F |w:7.7| |
Structure |
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