| Reaction Details |
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 | Report a problem with these data |
| Target | Corticotropin-releasing factor-binding protein |
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| Ligand | BDBM91415 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex |
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| EC50 | >53000±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Corticotropin-releasing factor-binding protein |
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| Name: | Corticotropin-releasing factor-binding protein |
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| Synonyms: | CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36143.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P24387 |
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| Residue: | 322 |
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| Sequence: | MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRC
LDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKG
EKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNL
FPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGI
GDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQ
LEPYELENPNGNSIGEFCLSGL
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| BDBM91415 |
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| n/a |
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| Name | BDBM91415 |
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| Synonyms: | 2-[6-(diethylamino)-7-methyl-7,8-dihydro-6H-[1,3]dioxolo[4,5-g][1]benzopyran-8-yl]-6-methoxyphenol | 2-[6-(diethylamino)-7-methyl-7,8-dihydro-6H-[1,3]dioxolo[4,5-g]chromen-8-yl]-6-methoxy-phenol | 2-[6-(diethylamino)-7-methyl-7,8-dihydro-6H-[1,3]dioxolo[4,5-g]chromen-8-yl]-6-methoxyphenol | MLS002702192 | SMR001565755 | cid_381395 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H27NO5 |
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| Mol. Mass. | 385.4535 |
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| SMILES | CCN(CC)C1Oc2cc3OCOc3cc2C(C1C)c1cccc(OC)c1O |
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| Structure | 
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