| Reaction Details |
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 | Report a problem with these data |
| Target | ATP-binding cassette sub-family B member 6 |
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| Ligand | BDBM47475 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response of Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for Cherry Pick01 |
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| EC50 | 210±n/a nM |
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| Citation |  PubChem, PC Dose Response of Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for Cherry Pick01 PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| ATP-binding cassette sub-family B member 6 |
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| Name: | ATP-binding cassette sub-family B member 6 |
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| Synonyms: | ABCB6 | ABCB6_HUMAN | ATP-binding cassette sub-family B member 6, mitochondrial | MTABC3 | PRP | UMAT |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 93896.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_9955963 |
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| Residue: | 842 |
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| Sequence: | MVTVGNYCEAEGPVGPAWMQDGLSPCFFFTLVPSTRMALGTLALVLALPCRRRERPAGAD
SLSWGAGPRISPYVLQLLLATLQAALPLAGLAGRVGTARGAPLPSYLLLASVLESLAGAC
GLWLLVVERSQARQRLAMGIWIKFRHSPGLLLLWTVAFAAENLALVSWNSPQWWWARADL
GQQVQFSLWVLRYVVSGGLFVLGLWAPGLRPQSYTLQVHEEDQDVERSQVRSAAQQSTWR
DFGRKLRLLSGYLWPRGSPALQLVVLICLGLMGLERALNVLVPIFYRNIVNLLTEKAPWN
SLAWTVTSYVFLKFLQGGGTGSTGFVSNLRTFLWIRVQQFTSRRVELLIFSHLHELSLRW
HLGRRTGEVLRIADRGTSSVTGLLSYLVFNVIPTLADIIIGIIYFSMFFNAWFGLIVFLC
MSLYLTLTIVVTEWRTKFRRAMNTQENATRARAVDSLLNFETVKYYNAESYEVERYREAI
IKYQGLEWKSSASLVLLNQTQNLVIGLGLLAGSLLCAYFVTEQKLQVGDYVLFGTYIIQL
YMPLNWFGTYYRMIQTNFIDMENMFDLLKEETEVKDLPGAGPLRFQKGRIEFENVHFSYA
DGRETLQDVSFTVMPGQTLALVGPSGAGKSTILRLLFRFYDISSGCIRIDGQDISQVTQA
SLRSHIGVVPQDTVLFNDTIADNIRYGRVTAGNDEVEAAAQAAGIHDAIMAFPEGYRTQV
GERGLKLSGGEKQRVAIARTILKAPGIILLDEATSALDTSNERAIQASLAKVCANRTTIV
VAHRLSTVVNADQILVIKDGCIVERGRHEALLSRGGVYADMWQLQQGQEETSEDTKPQTM
ER
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| BDBM47475 |
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| n/a |
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| Name | BDBM47475 |
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| Synonyms: | 2-[[(Z)-[2-[3-(diethylsulfamoyl)phenyl]-1,3-bis(oxidanylidene)isoquinolin-4-ylidene]methyl]amino]benzoic acid | 2-[[(Z)-[2-[3-(diethylsulfamoyl)phenyl]-1,3-diketo-4-isoquinolylidene]methyl]amino]benzoic acid | 2-[[(Z)-[2-[3-(diethylsulfamoyl)phenyl]-1,3-dioxo-4-isoquinolinylidene]methyl]amino]benzoic acid | 2-[[(Z)-[2-[3-(diethylsulfamoyl)phenyl]-1,3-dioxoisoquinolin-4-ylidene]methyl]amino]benzoic acid | MLS001002340 | SMR000368858 | cid_6108189 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H25N3O6S |
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| Mol. Mass. | 519.569 |
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| SMILES | CCN(CC)S(=O)(=O)c1cccc(c1)-n1c(O)c(C=Nc2ccccc2C(O)=O)c2ccccc2c1=O |w:19.20| |
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| Structure | 
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