| Reaction Details |
|---|
 | Report a problem with these data |
| Target | ATP-binding cassette sub-family B member 6 |
|---|
| Ligand | BDBM67355 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose Response of Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for Cherry Pick01 |
|---|
| EC50 | 62790±n/a nM |
|---|
| Citation |  PubChem, PC Dose Response of Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for Cherry Pick01 PubChem Bioassay(2012)[AID] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| ATP-binding cassette sub-family B member 6 |
|---|
| Name: | ATP-binding cassette sub-family B member 6 |
|---|
| Synonyms: | ABCB6 | ABCB6_HUMAN | ATP-binding cassette sub-family B member 6, mitochondrial | MTABC3 | PRP | UMAT |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 93896.51 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_9955963 |
|---|
| Residue: | 842 |
|---|
| Sequence: | MVTVGNYCEAEGPVGPAWMQDGLSPCFFFTLVPSTRMALGTLALVLALPCRRRERPAGAD
SLSWGAGPRISPYVLQLLLATLQAALPLAGLAGRVGTARGAPLPSYLLLASVLESLAGAC
GLWLLVVERSQARQRLAMGIWIKFRHSPGLLLLWTVAFAAENLALVSWNSPQWWWARADL
GQQVQFSLWVLRYVVSGGLFVLGLWAPGLRPQSYTLQVHEEDQDVERSQVRSAAQQSTWR
DFGRKLRLLSGYLWPRGSPALQLVVLICLGLMGLERALNVLVPIFYRNIVNLLTEKAPWN
SLAWTVTSYVFLKFLQGGGTGSTGFVSNLRTFLWIRVQQFTSRRVELLIFSHLHELSLRW
HLGRRTGEVLRIADRGTSSVTGLLSYLVFNVIPTLADIIIGIIYFSMFFNAWFGLIVFLC
MSLYLTLTIVVTEWRTKFRRAMNTQENATRARAVDSLLNFETVKYYNAESYEVERYREAI
IKYQGLEWKSSASLVLLNQTQNLVIGLGLLAGSLLCAYFVTEQKLQVGDYVLFGTYIIQL
YMPLNWFGTYYRMIQTNFIDMENMFDLLKEETEVKDLPGAGPLRFQKGRIEFENVHFSYA
DGRETLQDVSFTVMPGQTLALVGPSGAGKSTILRLLFRFYDISSGCIRIDGQDISQVTQA
SLRSHIGVVPQDTVLFNDTIADNIRYGRVTAGNDEVEAAAQAAGIHDAIMAFPEGYRTQV
GERGLKLSGGEKQRVAIARTILKAPGIILLDEATSALDTSNERAIQASLAKVCANRTTIV
VAHRLSTVVNADQILVIKDGCIVERGRHEALLSRGGVYADMWQLQQGQEETSEDTKPQTM
ER
|
|
|
|---|
| BDBM67355 |
|---|
| n/a |
|---|
| Name | BDBM67355 |
|---|
| Synonyms: | 2-benzylsulfonyl-5-chloro-N-(4-fluorophenyl)pyrimidine-4-carboxamide | 5-chloranyl-N-(4-fluorophenyl)-2-(phenylmethyl)sulfonyl-pyrimidine-4-carboxamide | 5-chloro-N-(4-fluorophenyl)-2-(phenylmethyl)sulfonyl-4-pyrimidinecarboxamide | MLS001116156 | SMR000625770 | cid_16446684 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H13ClFN3O3S |
|---|
| Mol. Mass. | 405.831 |
|---|
| SMILES | Fc1ccc(NC(=O)c2nc(ncc2Cl)S(=O)(=O)Cc2ccccc2)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
