| Reaction Details |
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 | Report a problem with these data |
| Target | DNA dC->dU-editing enzyme APOBEC-3A |
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| Ligand | BDBM91526 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SAR analysis of small molecule inhibitors of APOBEC3A DNA Deaminase via a fluorescence-based single-stranded DNA deaminase assay - Set 2 |
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| Temperature | 298.15±n/a K |
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| IC50 | 34500±n/a nM |
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| Comments | extracted |
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| Citation |  PubChem, PC SAR analysis of small molecule inhibitors of APOBEC3A DNA Deaminase via a fluorescence-based single-stranded DNA deaminase assay - Set 2 PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| DNA dC->dU-editing enzyme APOBEC-3A |
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| Name: | DNA dC->dU-editing enzyme APOBEC-3A |
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| Synonyms: | ABC3A_HUMAN | APOBEC3A | probable DNA dC->dU-editing enzyme APOBEC-3A |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 23013.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_21955158 |
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| Residue: | 199 |
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| Sequence: | MEASPASGPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAK
NLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHV
RLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLD
EHSQALSGRLRAILQNQGN
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| BDBM91526 |
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| n/a |
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| Name | BDBM91526 |
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| Synonyms: | 6-bromanyl-N-methyl-N-(phenylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide | 6-bromo-N-methyl-N-(phenylmethyl)-2-pyrazolo[1,5-a]pyrimidinecarboxamide | MLS-0471502.0001 | N-benzyl-6-bromo-N-methyl-pyrazolo[1,5-a]pyrimidine-2-carboxamide | N-benzyl-6-bromo-N-methylpyrazolo[1,5-a]pyrimidine-2-carboxamide | cid_2234293 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H13BrN4O |
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| Mol. Mass. | 345.194 |
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| SMILES | CN(Cc1ccccc1)C(=O)c1cc2ncc(Br)cn2n1 |
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| Structure | 
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