| Reaction Details |
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 | Report a problem with these data |
| Target | DNA dC->dU-editing enzyme APOBEC-3A |
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| Ligand | BDBM60899 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SAR analysis of small molecule inhibitors of APOBEC3A DNA Deaminase via a fluorescence-based single-stranded DNA deaminase assay - Set 2 |
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| Temperature | 298.15±n/a K |
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| IC50 | >99000±n/a nM |
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| Comments | extracted |
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| Citation |  PubChem, PC SAR analysis of small molecule inhibitors of APOBEC3A DNA Deaminase via a fluorescence-based single-stranded DNA deaminase assay - Set 2 PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| DNA dC->dU-editing enzyme APOBEC-3A |
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| Name: | DNA dC->dU-editing enzyme APOBEC-3A |
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| Synonyms: | ABC3A_HUMAN | APOBEC3A | probable DNA dC->dU-editing enzyme APOBEC-3A |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 23013.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_21955158 |
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| Residue: | 199 |
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| Sequence: | MEASPASGPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAK
NLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHV
RLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLD
EHSQALSGRLRAILQNQGN
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| BDBM60899 |
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| n/a |
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| Name | BDBM60899 |
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| Synonyms: | 4-propyl-1-sulfanylidene-2H-[1,2,4]triazolo[4,3-a]quinazolin-5-one | 4-propyl-1-thioxo-2H-[1,2,4]triazolo[4,3-a]quinazolin-5-one | MLS001170914 | SMR000588314 | US20230365568, Compound 21 | cid_2423905 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H12N4OS |
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| Mol. Mass. | 260.315 |
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| SMILES | CCCn1c2n[nH]c(=S)n2c2ccccc2c1=O |
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| Structure | 
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