| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Tyrosine-protein phosphatase non-receptor type 5 |
|---|
| Ligand | BDBM88721 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose response orthogonal assay of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a colorimetric intensity assay. |
|---|
| IC50 | 32800±n/a nM |
|---|
| Citation |  PubChem, PC Dose response orthogonal assay of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a colorimetric intensity assay. PubChem Bioassay(2012)[AID] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Tyrosine-protein phosphatase non-receptor type 5 |
|---|
| Name: | Tyrosine-protein phosphatase non-receptor type 5 |
|---|
| Synonyms: | PTN5_HUMAN | PTPN5 | Tyrosine-protein phosphatase non-receptor type 5 | Tyrosine-protein phosphatase non-receptor type 5 isoform a |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 63510.68 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_90652859 |
|---|
| Residue: | 565 |
|---|
| Sequence: | MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP
PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLV
SSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPED
RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQ
ERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLL
QAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR
GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYD
GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE
AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQ
TCEQYQFVHHVMSLYEKQLSHQSPE
|
|
|
|---|
| BDBM88721 |
|---|
| n/a |
|---|
| Name | BDBM88721 |
|---|
| Synonyms: | (4E)-4-[(2-nitro-4-pyrrolidin-1-ylsulfonyl-phenyl)hydrazinylidene]-4-thiophen-2-yl-butanoic acid | (4E)-4-[(2-nitro-4-pyrrolidin-1-ylsulfonylphenyl)hydrazinylidene]-4-thiophen-2-ylbutanoic acid | (4E)-4-[(2-nitro-4-pyrrolidinosulfonyl-phenyl)hydrazono]-4-(2-thienyl)butyric acid | (4E)-4-[[2-nitro-4-(1-pyrrolidinylsulfonyl)phenyl]hydrazinylidene]-4-thiophen-2-ylbutanoic acid | MLS000536464 | SMR000151450 | cid_9655853 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H20N4O6S2 |
|---|
| Mol. Mass. | 452.505 |
|---|
| SMILES | OC(=O)CC[C-](\N=[NH+]\c1ccc(cc1[N+]([O-])=O)S(=O)(=O)N1CCCC1)c1cccs1 |
|---|
| Structure | 
|
|---|
Search and Browse
