| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosine-protein phosphatase non-receptor type 5 |
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| Ligand | BDBM88769 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response orthogonal assay of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a colorimetric intensity assay. |
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| IC50 | 27000±n/a nM |
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| Citation |  PubChem, PC Dose response orthogonal assay of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a colorimetric intensity assay. PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Tyrosine-protein phosphatase non-receptor type 5 |
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| Name: | Tyrosine-protein phosphatase non-receptor type 5 |
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| Synonyms: | PTN5_HUMAN | PTPN5 | Tyrosine-protein phosphatase non-receptor type 5 | Tyrosine-protein phosphatase non-receptor type 5 isoform a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 63510.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_90652859 |
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| Residue: | 565 |
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| Sequence: | MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP
PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLV
SSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPED
RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQ
ERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLL
QAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR
GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYD
GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE
AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQ
TCEQYQFVHHVMSLYEKQLSHQSPE
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| BDBM88769 |
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| n/a |
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| Name | BDBM88769 |
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| Synonyms: | 4-[2-(dimethylamino)ethyl-[(4-phenoxyanilino)-sulfanylidenemethyl]amino]-1-piperidinecarboxylic acid ethyl ester | 4-[2-(dimethylamino)ethyl-[(4-phenoxyphenyl)thiocarbamoyl]amino]piperidine-1-carboxylic acid ethyl ester | MLS000689506 | SMR000311544 | cid_16195551 | ethyl 4-([2-(dimethylamino)ethyl]{[(4-phenoxyphenyl)amino]carbonothioyl}amino)piperidine-1-carboxylate | ethyl 4-[2-(dimethylamino)ethyl-[(4-phenoxyphenyl)carbamothioyl]amino]piperidine-1-carboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C25H34N4O3S |
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| Mol. Mass. | 470.627 |
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| SMILES | CCOC(=O)N1CCC(CC1)N(CCN(C)C)C(=S)Nc1ccc(Oc2ccccc2)cc1 |
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| Structure | 
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