| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin G/H synthase 1 [582-599] |
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| Ligand | BDBM17638 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzyme Inhibition Assay |
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| IC50 | 2.6e+2± 3.2e+2 nM |
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| Citation |  Bekhit, AA; Ashour, HM; Bekhit, Ael-D; Abdel-Rahman, HM; Bekhit, SA Synthesis of some pyrazolyl benzenesulfonamide derivatives as dual anti-inflammatory antimicrobial agents. J Enzyme Inhib Med Chem24:296-309 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin G/H synthase 1 [582-599] |
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| Name: | Prostaglandin G/H synthase 1 [582-599] |
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| Synonyms: | COX-1 | COX1 | Cyclooxygenase | Cyclooxygenase-1 | Cyclooxygenase-1 (COX-1) | PGH synthase 1 | PGH1_HUMAN | PGHS-1 | PHS 1 | PTGS1 | Prostaglandin G/H synthase 1 | Prostaglandin H2 synthase 1 | Prostaglandin-endoperoxide synthase 1 |
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| Type: | Protein |
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| Mol. Mass.: | 1879.89 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q6LCE7 |
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| Residue: | 18 |
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| Sequence: | |
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| BDBM17638 |
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| n/a |
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| Name | BDBM17638 |
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| Synonyms: | 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid | CHEMBL6 | Indocin | Indomethacin | US11478464, Compound Indomethacin | US11786535, Compound Indomethacin | US9271961, Indomethacin | indometacin |
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| Type | Small organic molecule |
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| Emp. Form. | C19H16ClNO4 |
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| Mol. Mass. | 357.788 |
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| SMILES | COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 |
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| Structure | 
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