Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetTryptophanase
LigandBDBM91689
Substrate/Competitorn/a
Meas. Tech.Enzyme Inhibition Assay
pH7.8±0
Temperature298.15±0 K
Ki 174000000±9000000 nM
Citation Scherzer, RGdalevsky, GYGoldgur, YCohen-Luria, RBittner, SParola, AH New tryptophanase inhibitors: towards prevention of bacterial biofilm formation. J Enzyme Inhib Med Chem24:350-5 (2009) [PubMed]  Article
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Tryptophanase
Name:Tryptophanase
Synonyms:L-tryptophan indole-lyase | TNAA_ECOLI | ind | tnaA
Type:Enzyme
Mol. Mass.:52770.85
Organism:Escherichia coli
Description:P0A853
Residue:471
Sequence:
MENFKHLPEPFRIRVIEPVKRTTRAYREEAIIKSGMNPFLLDSEDVFIDLLTDSGTGAVT
QSMQAAMMRGDEAYSGSRSYYALAESVKNIFGYQYTIPTHQGRGAEQIYIPVLIKKREQE
KGLDRSKMVAFSNYFFDTTQGHSQINGCTVRNVYIKEAFDTGVRYDFKGNFDLEGLERGI
EEVGPNNVPYIVATITSNSAGGQPVSLANLKAMYSIAKKYDIPVVMDSARFAENAYFIKQ
REAEYKDWTIEQITRETYKYADMLAMSAKKDAMVPMGGLLCMKDDSFFDVYTECRTLCVV
QEGFPTYGGLEGGAMERLAVGLYDGMNLDWLAYRIAQVQYLVDGLEEIGVVCQQAGGHAA
FVDAGKLLPHIPADQFPAQALACELYKVAGIRAVEIGSFLLGRDPKTGKQLPCPAELLRL
TIPRATYTQTHMDFIIEAFKHVKENAANIKGLTFTYEPKVLRHFTAKLKEV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM91689
n/a
NameBDBM91689
Synonyms:Alpha-amino-2-(9,10-anthraquinone)-popanoic acid
TypeSmall organic molecule
Emp. Form.C17H13NO4
Mol. Mass.295.2894
SMILESNC(Cc1ccc2C(=O)c3ccccc3C(=O)c2c1)C(O)=O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: