| Reaction Details |
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 | Report a problem with these data |
| Target | Cyclin-A2/Cyclin-dependent kinase 2 |
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| Ligand | BDBM91795 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | OctetRed |
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| pH | 7.5±n/a |
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| Temperature | 298.15±n/a K |
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| Kd | >100000±n/a nM |
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| Citation |  CSARdock, CD CDK2-CyclinA in CSAR_FULL_RELEASE_3JULY2012 CSAR1:0 (2012) |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Cyclin-A2/Cyclin-dependent kinase 2 |
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| Name: | Cyclin-A2/Cyclin-dependent kinase 2 |
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| Synonyms: | CDK2-CyclinA | CDK2/A | CDK2/Cyclin A | CDK2/Cyclin A2 | Cyclin A2/dependent kinase 2 | Cyclin-Dependent Kinase 2 (CDK2) | Cyclin-Dependent Kinase 2 (CDK2A) |
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| Type: | Protein Complex |
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| Mol. Mass.: | n/a |
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| Description: | Cdk2/Cyclin A kinase was purified from insect cells coinfected with Cyclin A/Cdk2 baculovirus. |
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| Components: | This complex has 2 components. |
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| Component 1 |
| Name: | Cyclin-dependent kinase 2 |
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| Synonyms: | CDK2 | CDK2-Kinase | CDK2_HUMAN | CDKN2 | Cell division protein kinase 2 | Cyclin-dependent kinase 2 (CDK2) | Protein cereblon/Cyclin-dependent kinase 2 | p33 protein kinase |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 33938.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P24941 |
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| Residue: | 298 |
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| Sequence: | MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS
HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY
STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF
PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
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| Component 2 |
| Name: | Cyclin-A2 |
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| Synonyms: | CCN1 | CCNA | CCNA1 | CCNA2 | CCNA2_HUMAN | Cyclin A | Cyclin-A |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 48550.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P20248 |
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| Residue: | 432 |
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| Sequence: | MLGNSAPGPATREAGSALLALQQTALQEDQENINPEKAAPVQQPRTRAALAVLKSGNPRG
LAQQQRPKTRRVAPLKDLPVNDEHVTVPPWKANSKQPAFTIHVDEAEKEAQKKPAESQKI
EREDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTMDMSIILEDEKPVSVNEVPDYHE
DIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYID
RFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLK
VLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAF
HLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHG
VSLLNPPETLNL
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| BDBM91795 |
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| n/a |
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| Name | BDBM91795 |
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| Synonyms: | CS47 |
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| Type | n/a |
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| Emp. Form. | C19H19ClN4O3S |
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| Mol. Mass. | 418.897 |
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| SMILES | COc1cc(OC)c(NC(=O)CSc2nnc(-c3ccccc3)n2C)cc1Cl |
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| Structure | 
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