| Reaction Details |
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 | Report a problem with these data |
| Target | Serum paraoxonase/arylesterase 1 |
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| Ligand | BDBM50174201 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Paraoxonase Activity Assay |
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| pH | 10.5±0 |
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| Temperature | 298.15±0 K |
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| Ki | 805000±0.0 nM |
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| IC50 | 1639000±0.0 nM |
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| Citation |  Ekinci, D; Beydemir, S Effect of some analgesics on paraoxonase-1 purified from human serum. J Enzyme Inhib Med Chem24:1034-9 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Serum paraoxonase/arylesterase 1 |
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| Name: | Serum paraoxonase/arylesterase 1 |
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| Synonyms: | A-esterase 1 | Aromatic esterase 1 | K-45 | PON | PON 1 | PON1 | PON1_HUMAN | Paraoxonase (PON1) | Paraoxonase (hPON1) | Paraoxonase 1 (PON1) | Serum aryldialkylphosphatase 1 | Serum paraoxonase 1 (PON1) |
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| Type: | Enzyme |
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| Mol. Mass.: | 39719.73 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P27169 |
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| Residue: | 355 |
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| Sequence: | MAKLIALTLLGMGLALFRNHQSSYQTRLNALREVQPVELPNCNLVKGIETGSEDLEILPN
GLAFISSGLKYPGIKSFNPNSPGKILLMDLNEEDPTVLELGITGSKFDVSSFNPHGISTF
TDEDNAMYLLVVNHPDAKSTVELFKFQEEEKSLLHLKTIRHKLLPNLNDIVAVGPEHFYG
TNDHYFLDPYLQSWEMYLGLAWSYVVYYSPSEVRVVAEGFDFANGINISPDGKYVYIAEL
LAHKIHVYEKHANWTLTPLKSLDFNTLVDNISVDPETGDLWVGCHPNGMKIFFYDSENPP
ASEVLRIQNILTEEPKVTQVYAENGTVLQGSTVASVYKGKLLIGTVFHKALYCEL
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| BDBM50174201 |
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| n/a |
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| Name | BDBM50174201 |
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| Synonyms: | ARTHROTEC | GP 45840 | SOLARAZE | Sodium; [2-(2,6-dichloro-phenylamino)-phenyl]-acetate | US11173137, Compound Diclofenac | VOLTAREN | VOLTAREN-XR | diclofenac sodium | sodium 2-(2-(2,6-dichlorophenylamino)phenyl)acetate |
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| Type | Small organic molecule |
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| Emp. Form. | C14H10Cl2NO2 |
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| Mol. Mass. | 295.141 |
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| SMILES | [O-]C(=O)Cc1ccccc1Nc1c(Cl)cccc1Cl |
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| Structure | 
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