| Reaction Details |
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 | Report a problem with these data |
| Target | Pancreatic alpha-amylase |
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| Ligand | BDBM92363 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzymatic Activity Assay |
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| pH | 7±0 |
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| Temperature | 310.15±0 K |
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| Ki | 3.42e+5± 7.1e+4 nM |
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| IC50 | 1.50e+5± 8.1e+3 nM |
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| Citation |  Senger, MR; Gomes, Lda C; Ferreira, SB; Kaiser, CR; Ferreira, VF; Silva, FP Kinetics Studies on the Inhibition Mechanism of Pancreatic α-Amylase by Glycoconjugated 1H-1,2,3-Triazoles: A New Class of Inhibitors with Hypoglycemiant Activity. Chembiochem13:1584-93 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Pancreatic alpha-amylase |
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| Name: | Pancreatic alpha-amylase |
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| Synonyms: | 1,4-alpha-D-glucan glucanohydrolase | AMY2 | AMYP_PIG | Pancreatic α-amylase | Pancreatic α-amylase |
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| Type: | Protein |
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| Mol. Mass.: | 57088.07 |
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| Organism: | Sus scrofa (Pig) |
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| Description: | P00690 |
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| Residue: | 511 |
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| Sequence: | MKLFLLLSAFGFCWAQYAPQTQSGRTSIVHLFEWRWVDIALECERYLGPKGFGGVQVSPP
NENIVVTNPSRPWWERYQPVSYKLCTRSGNENEFRDMVTRCNNVGVRIYVDAVINHMCGS
GAAAGTGTTCGSYCNPGNREFPAVPYSAWDFNDGKCKTASGGIESYNDPYQVRDCQLVGL
LDLALEKDYVRSMIADYLNKLIDIGVAGFRIDASKHMWPGDIKAVLDKLHNLNTNWFPAG
SRPFIFQEVIDLGGEAIQSSEYFGNGRVTEFKYGAKLGTVVRKWSGEKMSYLKNWGEGWG
FMPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKVAVGFMLAHPYGFTRVMSSYRWA
RNFVNGQDVNDWIGPPNNNGVIKEVTINADTTCGNDWVCEHRWRQIRNMVWFRNVVDGQP
FANWWANGSNQVAFGRGNRGFIVFNNDDWQLSSTLQTGLPGGTYCDVISGDKVGNSCTGI
KVYVSSDGTAQFSISNSAEDPFIAIHAESKL
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| BDBM92363 |
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| n/a |
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| Name | BDBM92363 |
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| Synonyms: | GPESB02 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H25N3O4 |
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| Mol. Mass. | 335.3981 |
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| SMILES | CO[C@@H]1O[C@H](Cn2cc(nn2)C2=CCCCC2)[C@@H]2OC(C)(C)OC12 |r,t:12| |
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| Structure | 
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