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TargetTrehalose synthase/amylase TreS
LigandBDBM50182801
Substrate/Competitorn/a
Meas. Tech.Inhibition Assay
Ki 1.40e+5±n/a nM
Citation Zhang, R; Pan, YT; He, S; Lam, M; Brayer, GD; Elbein, AD; Withers, SG Mechanistic analysis of trehalose synthase from Mycobacterium smegmatis. J Biol Chem286:35601-9 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Trehalose synthase/amylase TreS
Name:Trehalose synthase/amylase TreS
Synonyms:Maltose alpha-D-glucosyltransferase | TRES_MYCTO | Trehalose Synthase (TreS) | treS
Type:Protein
Mol. Mass.:68564.96
Organism:Mycobacterium tuberculosis
Description:P9WQ18
Residue:601
Sequence:
MNEAEHSVEHPPVQGSHVEGGVVEHPDAKDFGSAAALPADPTWFKHAVFYEVLVRAFFDA
SADGSGDLRGLIDRLDYLQWLGIDCIWLPPFYDSPLRDGGYDIRDFYKVLPEFGTVDDFV
ALVDAAHRRGIRIITDLVMNHTSESHPWFQESRRDPDGPYGDYYVWSDTSERYTDARIIF
VDTEESNWSFDPVRRQFYWHRFFSHQPDLNYDNPAVQEAMIDVIRFWLGLGIDGFRLDAV
PYLFEREGTNCENLPETHAFLKRVRKVVDDEFPGRVLLAEANQWPGDVVEYFGDPNTGGD
ECHMAFHFPLMPRIFMAVRRESRFPISEIIAQTPPIPDMAQWGIFLRNHDELTLEMVTDE
ERDYMYAEYAKDPRMKANVGIRRRLAPLLDNDRNQIELFTALLLSLPGSPVLYYGDEIGM
GDVIWLGDRDGVRIPMQWTPDRNAGFSTANPGRLYLPPSQDPVYGYQAVNVEAQRDTSTS
LLNFTRTMLAVRRRHPAFAVGAFQELGGSNPSVLAYVRQVAGDDGDTVLCVNNLSRFPQP
IELDLQQWTNYTPVELTGHVEFPRIGQVPYLLTLPGHGFYWFQLTTHEVGAPPTCGGERR
L
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50182801
n/a
NameBDBM50182801
Synonyms:(3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol, 8 | (3R,4R,5R)-5-(hydroxymethyl)piperidine-3,4-diol | 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE | AFEGOSTAT TARTRATE | CHEMBL206468 | D-Isofagomine | US10081601, Example 1.1 | US9796680, Example Table2.1 | isofagomine
TypeSmall organic molecule
Emp. Form.C6H13NO3
Mol. Mass.147.1723
SMILESOC[C@H]1CNC[C@@H](O)[C@@H]1O |r|
Structure
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