| Reaction Details |
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 | Report a problem with these data |
| Target | Phosphoethanolamine N-methyltransferase 1 |
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| Ligand | BDBM50308984 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Calorimetric (ITC) Assay |
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| pH | 7.5±0 |
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| Temperature | 298.15±0 K |
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| Kd | 2.5e+3± 1e+2 nM |
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| Citation |  Lee, SG; Haakenson, W; McCarter, JP; Williams, DJ; Hresko, MC; Jez, JM Thermodynamic evaluation of ligand binding in the plant-like phosphoethanolamine methyltransferases of the parasitic nematode Haemonchus contortus. J Biol Chem286:38060-8 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Phosphoethanolamine N-methyltransferase 1 |
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| Name: | Phosphoethanolamine N-methyltransferase 1 |
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| Synonyms: | Phosphoehtnaolamine Methyltransferases 1 (PMT1) |
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| Type: | Enzyme |
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| Mol. Mass.: | 53531.36 |
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| Organism: | Caenorhabditis elegans |
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| Description: | Q86NB3 |
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| Residue: | 475 |
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| Sequence: | MSTDQQSSVEDQTVAMVNVRRANFKSFWDKYSDKPDTNSMMLNHSAEELESSDRADILAS
LPLLHNKDVVDIGAGIGRFTTVLAETARWVLSTDFIDSFIKKNQERNAHLGNINYQVGDA
VGLKMESNSVDLVFTNWLMMYLSDEETVEFIFNCMRWLRSHGIVHLRESCSEPSTGRSKA
KSMHDTANANPTHYRFSSLYINLLRAIRYRDVDNKLWRFNVQWSCSVPTYIKRSNNWRQV
HWLAEKVPAEDGAKGTSFNELVELIKNTWQNEQEAWDAKLDDEKYVWTDKVFSSALTSLP
SNSTFFLYTPRTVSPYCHINAHTLAETFNANVWNTEIIPEYYRTSLTKSNNLKDQRVRFG
WNQSLTDSVTYWQQKDALFDVFVATEFLSTVDDETIRQLPNVMSDGAKFITLEPVDEVNE
AEMKQRIQELGYTLKSFTDVTDQCIEAQEQYFKDHEQLRDEKVIRKNWVLLELTH
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| BDBM50308984 |
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| n/a |
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| Name | BDBM50308984 |
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| Synonyms: | AdoCys | CHEMBL597532 | S-Adenosylhomocysteine |
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| Type | Small organic molecule |
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| Emp. Form. | C14H20N6O5S |
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| Mol. Mass. | 384.411 |
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| SMILES | N[C@H](CCSC[C@@H]1O[C@@H]([C@@H](O)[C@H]1O)n1cnc2c(N)ncnc12)C(O)=O |r| |
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| Structure | 
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