Reaction Details |
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Target | Acid phosphatase |
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Ligand | BDBM92476 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Inhibitor Screening Assay |
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Ki | 3.27e+3± 8.5e+2 nM |
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Citation | McRae, S; Pagliai, FA; Mohapatra, NP; Gener, A; Mahmou, AS; Gunn, JS; Lorca, GL; Gonzalez, CF Inhibition of AcpA phosphatase activity with ascorbate attenuates Francisella tularensis intramacrophage survival. J Biol Chem285:5171-7 (2010) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Acid phosphatase |
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Name: | Acid phosphatase |
Synonyms: | Acid phosphatase (acpA) | Acid phosphatase (acpB) | Acid phosphatase (acpC) |
Type: | Enzyme |
Mol. Mass.: | 22350.38 |
Organism: | Francisella tularensis |
Description: | Q5NIC0 |
Residue: | 194 |
Sequence: | MTQQQVISYYESTAHENEVELILARAKKIIQAQQSLQGNAIVLDIDETALNHYYSLKLAG
FPQGENHTIWNELLSRTDAYPIKATLDFYLYCLTSGLKVFFISARFAQYLESTKQALRNA
GYVNFEDVFVFPENIEQYNSKDFKNFKAERRAYIESLGYKILISIGDQSSDLLGGYTLYT
LQLPNYLYGENSRF
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BDBM92476 |
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n/a |
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Name | BDBM92476 |
Synonyms: | (+)-5,6-O-Isopropylidene-L-ascorbic acid |
Type | Small organic molecule |
Emp. Form. | C9H12O6 |
Mol. Mass. | 216.188 |
SMILES | CC1(C)OC[C@H](O1)[C@H]1OC(=O)C(=O)C1O |
Structure |
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