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TargetAcid phosphatase
LigandBDBM92478
Substrate/Competitorn/a
Meas. Tech.Inhibitor Screening Assay
Ki 3.42e+5± 5.0e+4 nM
Citation McRae, SPagliai, FAMohapatra, NPGener, AMahmou, ASGunn, JSLorca, GLGonzalez, CF Inhibition of AcpA phosphatase activity with ascorbate attenuates Francisella tularensis intramacrophage survival. J Biol Chem285:5171-7 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Acid phosphatase
Name:Acid phosphatase
Synonyms:Acid phosphatase (acpA) | Acid phosphatase (acpB) | Acid phosphatase (acpC)
Type:Enzyme
Mol. Mass.:22350.38
Organism:Francisella tularensis
Description:Q5NIC0
Residue:194
Sequence:
MTQQQVISYYESTAHENEVELILARAKKIIQAQQSLQGNAIVLDIDETALNHYYSLKLAG
FPQGENHTIWNELLSRTDAYPIKATLDFYLYCLTSGLKVFFISARFAQYLESTKQALRNA
GYVNFEDVFVFPENIEQYNSKDFKNFKAERRAYIESLGYKILISIGDQSSDLLGGYTLYT
LQLPNYLYGENSRF
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM92478
n/a
NameBDBM92478
Synonyms:Atracurium besylate | CHEMBL1360
TypeMolecule
Emp. Form.C53H72N2O12
Mol. Mass.929.1439
SMILESCOc1ccc(CC2c3cc(OC)c(OC)cc3CC[N+]2(C)CCC(=O)OCCCCCOC(=O)CC[N+]2(C)CCc3cc(OC)c(OC)cc3C2Cc2ccc(OC)c(OC)c2)cc1OC
Structure
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