Reaction Details |
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Target | Acid phosphatase |
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Ligand | BDBM7462 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Inhibitor Screening Assay |
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Ki | 1.90e+5± 3.0e+4 nM |
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Citation | McRae, S; Pagliai, FA; Mohapatra, NP; Gener, A; Mahmou, AS; Gunn, JS; Lorca, GL; Gonzalez, CF Inhibition of AcpA phosphatase activity with ascorbate attenuates Francisella tularensis intramacrophage survival. J Biol Chem285:5171-7 (2010) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Acid phosphatase |
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Name: | Acid phosphatase |
Synonyms: | Acid phosphatase (acpA) | Acid phosphatase (acpB) | Acid phosphatase (acpC) |
Type: | Enzyme |
Mol. Mass.: | 22350.38 |
Organism: | Francisella tularensis |
Description: | Q5NIC0 |
Residue: | 194 |
Sequence: | MTQQQVISYYESTAHENEVELILARAKKIIQAQQSLQGNAIVLDIDETALNHYYSLKLAG
FPQGENHTIWNELLSRTDAYPIKATLDFYLYCLTSGLKVFFISARFAQYLESTKQALRNA
GYVNFEDVFVFPENIEQYNSKDFKNFKAERRAYIESLGYKILISIGDQSSDLLGGYTLYT
LQLPNYLYGENSRF
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BDBM7462 |
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n/a |
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Name | BDBM7462 |
Synonyms: | 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one | 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-chromen-4-one | CHEMBL150 | Kaempferol (18) | Kaempferol (Kmp) | cid_5280863 | kaempferol |
Type | Small organic molecule |
Emp. Form. | C15H10O6 |
Mol. Mass. | 286.2363 |
SMILES | Oc1ccc(cc1)-c1oc2cc(O)cc(O)c2c(=O)c1O |
Structure |
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