| Reaction Details |
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 | Report a problem with these data |
| Target | Envelope glycoprotein gp160 |
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| Ligand | BDBM279180 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Infectivity Assay |
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| EC50 | 550±n/a nM |
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| Citation |  Pendri, A; Li, G; Bender, JA; Yang, Z; Wang, AX; Beno, BR; Fridell, RA; Belema, M; Meanwell, NA; Gentles, RG Inhibitors of human immunodeficiency virus replication US Patent US10035760 Publication Date 7/31/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| Envelope glycoprotein gp160 |
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| Name: | Envelope glycoprotein gp160 |
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| Synonyms: | Env polyprotein | NL4-3 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 97031.14 |
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| Organism: | Human immunodeficiency virus type 1 (isolate BRU/LAI group M subtypeB) (HIV-1) |
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| Description: | n/a |
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| Residue: | 854 |
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| Sequence: | MRVKEKYQHLWRWGWKWGTMLLGILMICSATEKLWVTVYYGVPVWKEATTTLFCASDAKA
YDTEVHNVWATHACVPTDPNPQEVVLVNVTENFNMWKDDMVEQMHEDIISLWDQSLKPCV
KLTPLCVSLKCTDLKNDTNTNSSSGRMIMEKGEIKNCSFNISTSIRDKVQKEYAFFYKLD
IVPIDNTSYRLISCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNNKTFNGTGPCTNV
STVQCTHGIRPVVSTQLLLNGSLAEEDVVIRSANFTDNAKTIIVQLNTSVEINCTRPNNN
TRKSIRIQRGPGRAFVTIGKIGNMRQAHCNISRAKWNATLKQIASKLREQFGNNKTIIFK
QSSGGDPEIVTHSFNCGGEFFYCNSTQLFNSTWFNSTWSTEGSNNTEGSDTITLPCRIKQ
FINMWQEVGKAMYAPPISGQIRCSSNITGLLLTRDGGNNNNGSEIFRPGGGDMRDNWRSE
LYKYKVVKIEPLGVAPTKAKRRVVQREKRAVGIGALFLGFLGAAGSTMGAASMTLTVQAR
QLLSDIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARILAVERYLKDQQLLGIWGCSGKL
ICTTAVPWNASWSNKSLEQIWNNMTWMEWDREINNYTSLIHSLIEESQNQQEKNEQELLE
LDKWASLWNWFNITNWLWYIKLFIMIVGGLVGLRIVFAVLSIVNRVRQGYSPLSFQTHLP
IPRGPDRPEGIEEEGGERGRDRSIRLVNGSLALIWDDLRSLCLFSYHRLRDLLLIVTRIV
ELLGRRGWEALKYWWNLLQYWSQELKNSAVNLLNATAIAVAEGTDRVIEVLQAAYRAIRH
IPRRIRQGLERILL
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| BDBM279180 |
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| n/a |
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| Name | BDBM279180 |
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| Synonyms: | US10035760, Example 8 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H25N3O7S |
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| Mol. Mass. | 511.547 |
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| SMILES | COc1ccc(cc1)S(=O)(=O)NC(=O)N[C@@H](Cc1ccccc1)C(=O)N(C)c1ccc2OCOc2c1 |r| |
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| Structure | 
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