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Target2'-deoxynucleoside 5'-phosphate N-hydrolase 1
LigandBDBM92537
Substrate/Competitorn/a
Meas. Tech.Inhibition Assay
Ki 2.0e+4±n/a nM
Citation Dupouy, CZhang, CPadilla, APochet, SKaminski, PA Probing the active site of the deoxynucleotide N-hydrolase Rcl encoded by the rat gene c6orf108. J Biol Chem285:41806-14 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
Name:2'-deoxynucleoside 5'-phosphate N-hydrolase 1
Synonyms:DNPH1_RAT | Deoxyribonucleoside 5'-monophosphate N-glycosidase (Rcl) | Deoxyribonucleoside 5'-monophosphate N-glycosidase (Rcl) D69N | Deoxyribonucleoside 5'-monophosphate N-glycosidase (Rcl) E93Q | Deoxyribonucleoside 5'-monophosphate N-glycosidase (Rcl) S117A | Deoxyribonucleoside 5'-monophosphate N-glycosidase (Rcl) Y13F | Dnph1 | Rcl | c-Myc-responsive protein Rcl
Type:Enzyme
Mol. Mass.:17775.23
Organism:Rattus norvegicus (Rat)
Description:O35820
Residue:163
Sequence:
MAASGEQAPCSVYFCGSIRGGREDQALYARIVSRLRRYGKVLTEHVADAELEPLGEEAAG
GDQFIHEQDLNWLQQADVVVAEVTQPSLGVGYELGRAVALGKPILCLFRPQSGRVLSAMI
RGAADGSRFQVWDYAEGEVETMLDRYFEAYLPQKTASSSHPSA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM92537
n/a
NameBDBM92537
Synonyms:GMP
TypeSmall molecule
Emp. Form.C10H12N5O8P
Mol. Mass.361.2058
SMILESNc1nc2n(cnc2c(=O)[nH]1)C1OC(COP([O-])([O-])=O)C(O)C1O
Structure
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