| Reaction Details |
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 | Report a problem with these data |
| Target | Cyclin-dependent kinase 2 |
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| Ligand | BDBM67612 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| IC50 | 4.6e+4± 1.0e+4 nM |
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| Citation |  Martin, MP; Alam, R; Betzi, S; Ingles, DJ; Zhu, JY; Schönbrunn, E A Novel Approach to the Discovery of Small-Molecule Ligands of CDK2. Chembiochem13:2128-36 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cyclin-dependent kinase 2 |
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| Name: | Cyclin-dependent kinase 2 |
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| Synonyms: | CDK2 | CDK2-Kinase | CDK2_HUMAN | CDKN2 | Cell division protein kinase 2 | Cyclin-dependent kinase 2 (CDK2) | Protein cereblon/Cyclin-dependent kinase 2 | p33 protein kinase |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 33938.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P24941 |
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| Residue: | 298 |
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| Sequence: | MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS
HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY
STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF
PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
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| BDBM67612 |
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| n/a |
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| Name | BDBM67612 |
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| Synonyms: | 2-(2-pyridinyl)indene-1,3-dione | 2-(2-pyridyl)indane-1,3-dione | 2-(2-pyridyl)indane-1,3-quinone | 2-pyridin-2-ylindene-1,3-dione | MLS000719861 | SMR000304390 | cid_238065 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H9NO2 |
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| Mol. Mass. | 223.2268 |
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| SMILES | O=C1C(C(=O)c2ccccc12)c1ccccn1 |
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| Structure | 
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