Reaction Details |
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Target | Cytochrome P450 130 |
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Ligand | BDBM31774 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Binding Assay |
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Kd | 6.1e+3± 2e+2 nM |
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Citation | Podust, LM; Ouellet, H; von Kries, JP; de Montellano, PR Interaction of Mycobacterium tuberculosis CYP130 with heterocyclic arylamines. J Biol Chem284:25211-9 (2009) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Cytochrome P450 130 |
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Name: | Cytochrome P450 130 |
Synonyms: | CP130_MYCTU | Cytochrome P450 130 (G243A) | Putative cytochrome P450 130 | cyp130 |
Type: | Enzyme |
Mol. Mass.: | 44574.98 |
Organism: | Mycobacterium tuberculosis |
Description: | P9WPN5 |
Residue: | 405 |
Sequence: | MTSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAAR
DHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTV
RKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVD
GATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTM
VTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRD
VTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAA
RMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS
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BDBM31774 |
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n/a |
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Name | BDBM31774 |
Synonyms: | CHEMBL104 | Canesten | Clotrimazole | Lotrimin | Mycelex | US9138393, Clotrimazole | cid_2812 |
Type | Small organic molecule |
Emp. Form. | C22H17ClN2 |
Mol. Mass. | 344.837 |
SMILES | Clc1ccccc1C(c1ccccc1)(c1ccccc1)n1ccnc1 |
Structure |
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