| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Phosphatidylcholine-sterol acyltransferase |
|---|
| Ligand | BDBM92616 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Enzyme Assay |
|---|
| pH | 7.5±0 |
|---|
| Temperature | 277.15±0 K |
|---|
| IC50 | 60±0.0 nM |
|---|
| Citation |  Jauhiainen, M; Yuan, w; Gelb, MH; Dolphin, J Human Plasma Lecithin-Cholesterol Acyltransferase J Biol Chem264:1963-1967 (1989) |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Phosphatidylcholine-sterol acyltransferase |
|---|
| Name: | Phosphatidylcholine-sterol acyltransferase |
|---|
| Synonyms: | LCAT | LCAT_HUMAN | Lecithin-cholesterol acyltransferase (LCAT) | Phosphatidylcholine-sterol acyltransferase | Phospholipid-cholesterol acyltransferase |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 49573.79 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P04180 |
|---|
| Residue: | 440 |
|---|
| Sequence: | MGPPGSPWQWVTLLLGLLLPPAAPFWLLNVLFPPHTTPKAELSNHTRPVILVPGCLGNQL
EAKLDKPDVVNWMCYRKTEDFFTIWLDLNMFLPLGVDCWIDNTRVVYNRSSGLVSNAPGV
QIRVPGFGKTYSVEYLDSSKLAGYLHTLVQNLVNNGYVRDETVRAAPYDWRLEPGQQEEY
YRKLAGLVEEMHAAYGKPVFLIGHSLGCLHLLYFLLRQPQAWKDRFIDGFISLGAPWGGS
IKPMLVLASGDNQGIPIMSSIKLKEEQRITTTSPWMFPSRMAWPEDHVFISTPSFNYTGR
DFQRFFADLHFEEGWYMWLQSRDLLAGLPAPGVEVYCLYGVGLPTPRTYIYDHGFPYTDP
VGVLYEDGDDTVATRSTELCGLWQGRQPQPVHLLPLHGIQHLNMVFSNLTLEHINAILLG
AYRQGPPASPTASPEPPPPE
|
|
|
|---|
| BDBM92616 |
|---|
| n/a |
|---|
| Name | BDBM92616 |
|---|
| Synonyms: | Difluoroketone phospholipid analogue, 4 |
|---|
| Type | n/a |
|---|
| Emp. Form. | C25H48F2NO7P |
|---|
| Mol. Mass. | 543.6217 |
|---|
| SMILES | CCCCCCCC(=O)OCC(COP([O-])(=O)OCC[N+](C)(C)C)CC(=O)C(F)(F)CCCCCC |
|---|
| Structure | 
|
|---|
Search and Browse
