| Reaction Details |
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 | Report a problem with these data |
| Target | Isochorismatase domain-containing protein |
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| Ligand | BDBM50026863 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | GDH-Coupled Nicotinamidase Assay |
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| Ki | 110±10 nM |
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| Citation |  French, JB; Cen, Y; Vrablik, TL; Xu, P; Allen, E; Hanna-Rose, W; Sauve, AA Characterization of nicotinamidases: steady state kinetic parameters, classwide inhibition by nicotinaldehydes, and catalytic mechanism. Biochemistry49:10421-39 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Isochorismatase domain-containing protein |
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| Name: | Isochorismatase domain-containing protein |
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| Synonyms: | Nicotinamidase (CePNC1) | Nicotine deamidase |
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| Type: | Enzyme |
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| Mol. Mass.: | 37789.90 |
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| Organism: | Caenorhabditis elegans |
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| Description: | Q9N426 |
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| Residue: | 335 |
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| Sequence: | MFPCPKLIFPRLMAFIGLIWMVHSDNSATTNNNTILGNQSLEAIPEQLSELTGITVEESE
RIMESWLGNRQLDLRTSVLFDQEVLSRLRSLRVALLVVDFQNDFVDGSLKIGDGDAGQEP
SSAITPLNELLQLSSWDLVVYTKDWHPHNHISFLSQAHNSDRVMDEKDENKTLGFFDSVQ
FLKPIKTEQVLYPDHCIQKSWGSDIHPEIYIADNAEYIMKGVDPYLDSYSAFNDNNGRSK
TELEDLLRRENIDAVVIAGLAYDICVRFTCLDAVKQNFLAAVIPECSAGLTKKGIEESEM
AFKKQGVAMISKDEARGITEGGFLPREWVQRIVKK
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| BDBM50026863 |
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| n/a |
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| Name | BDBM50026863 |
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| Synonyms: | CHEMBL268493 | Nicotinamidase Inhibitor, 16 | PncA Inhibitor, 2 | Pyridine-3-carbaldehyde |
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| Type | Small organic molecule |
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| Emp. Form. | C6H5NO |
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| Mol. Mass. | 107.11 |
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| SMILES | O=Cc1cccnc1 |
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| Structure | 
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