Reaction Details |
| Report a problem with these data |
Target | Isochorismatase domain-containing protein |
---|
Ligand | BDBM92855 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | GDH-Coupled Nicotinamidase Assay |
---|
Ki | 440±22 nM |
---|
Citation | French, JB; Cen, Y; Vrablik, TL; Xu, P; Allen, E; Hanna-Rose, W; Sauve, AA Characterization of nicotinamidases: steady state kinetic parameters, classwide inhibition by nicotinaldehydes, and catalytic mechanism. Biochemistry49:10421-39 (2010) [PubMed] Article |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Isochorismatase domain-containing protein |
---|
Name: | Isochorismatase domain-containing protein |
Synonyms: | Nicotinamidase (CePNC2) |
Type: | Enzyme |
Mol. Mass.: | 36083.31 |
Organism: | Caenorhabditis elegans |
Description: | Q7YTI0 |
Residue: | 316 |
Sequence: | MGVVQNEQDIREKMKNELISLVNEIDLIPELDRLLDDFIENKTWNEDTQELFTRVVLKPF
TTLRTSLLVVDFQNDFVTGSLSIKEGDAEQDPLEALPHVNNLLENLNWNMIVYTQDWHPS
NHISFFEHARNPDRELAPEDKSRKLRPFDIVRFVKPVSTIQVLYPSHCIQGGWGSQLHLG
LQRIDGAHYIKKGADVYVDAYSAFSDNCGIKQSELEMLLRKNDINAVIGCGLAYDICVMH
TLKDASKHGFLTCIVKSGSKGLSSLKMDEANKMFQKRGVAIIDDEMAQLISRREAFPIEW
IRLLVHQAQSELHGKK
|
|
|
BDBM92855 |
---|
n/a |
---|
Name | BDBM92855 |
Synonyms: | Nicotinamidase Inhibitor, 22 |
Type | Small molecule |
Emp. Form. | C7H7NO2 |
Mol. Mass. | 137.136 |
SMILES | COc1ccncc1C=O |
Structure |
|