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TargetNS3 protein
LigandBDBM92891
Substrate/Competitorn/a
Meas. Tech.Competitive Inhibition Assay
Ki 180±58 nM
Citation Dahl GArenas OGDanielson UH Hepatitis C virus NS3 protease is activated by low concentrations of protease inhibitors. Biochemistry 48:11592-602 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
NS3 protein
Name:NS3 protein
Synonyms:n/a
Type:Protein
Mol. Mass.:45665.89
Organism:Hepatitis C virus
Description:Q04045
Residue:428
Sequence:
VFTDNSSPPAVPQSFQVAHLHAPTGSGKSTKVPAAYAAQGYKVLVLNPSVAATLGFGAYM
SKAHGVDPNIRTGVRTITTGSPITYSTYGKFLADGGCSGGAYDIIICDECHSTDATSILG
IGTVLDQAETAGARLVVLATATPPGSVTVSHPNIEEVALSTTGEIPFYGKAIPLEVIKGG
RHLIFCHSKKKCDELAAKLVALGINAVAYYRGLDVSVIPTSGDVVVVSTDALMTGFTGDF
DSVIDCNTCVTQTVDFSLDPTFTIETTTLPQDAVSRTQRRGRTGRGKPGIYRFVAPGERP
SGMFDSSVLCECYDAGCAWYELTPAETTVRLRAYMNTPGLPVCQDHLEFWEGVFTGLTHI
DAHFLSQTKQSGENFPYLVAYQATVCARAQAPPPSWDQMWKCLIRLKPTLHGPTPLLYRL
GAVQNEVT
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM92891
n/a
NameBDBM92891
Synonyms:NS3 Protease Inhibitor, 2
TypeSmall molecule
Emp. Form.C33H42N4O10S
Mol. Mass.686.772
SMILESOC(=O)CC[C@H](NC(=O)[C@@H](NC(=O)CCC(O)=O)C1CCCCC1)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CS)C(O)=O |r|
Structure
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