Reaction Details |
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Target | Translocator protein |
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Ligand | BDBM279579 |
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Substrate/Competitor | n/a |
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Meas. Tech. | [3H]PK 11195 radio-assay |
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Ki | 1506±n/a nM |
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Citation | Gavish, M; Veenman, JA; Shterenberg, A; Marek, I; Vainshtein, A; Avital, A Quinazoline scaffold based compounds, pharmaceutical compositions and methods of use thereof US Patent US10035780 Publication Date 7/31/2018 |
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More Info.: | Get all data from this article, Assay Method |
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Translocator protein |
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Name: | Translocator protein |
Synonyms: | BZRP | MBR | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor-related protein | Peripheral-type benzodiazepine receptor | TSPO | TSPO_HUMAN |
Type: | Enzyme |
Mol. Mass.: | 18834.74 |
Organism: | Homo sapiens (Human) |
Description: | P30536 |
Residue: | 169 |
Sequence: | MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAM
GYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAA
ATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE
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BDBM279579 |
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n/a |
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Name | BDBM279579 |
Synonyms: | US10035780, Compound 3 |
Type | Small organic molecule |
Emp. Form. | C19H17Cl2N3O2 |
Mol. Mass. | 390.263 |
SMILES | CCN(CC)C(=O)Oc1nc(nc2ccccc12)-c1c(Cl)cccc1Cl |
Structure |
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