| Reaction Details |
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 | Report a problem with these data |
| Target | Bifunctional aspartokinase/homoserine dehydrogenase 1 |
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| Ligand | BDBM92993 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| Ki | 30000000±7000000 nM |
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| Citation |  Angeles, TS; Hunsley, JR; Viola, RE Reversal of enzyme regiospecificity with alternative substrates for aspartokinase I from Escherichia coli. Biochemistry31:799-805 (1992) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Bifunctional aspartokinase/homoserine dehydrogenase 1 |
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| Name: | Bifunctional aspartokinase/homoserine dehydrogenase 1 |
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| Synonyms: | AK1H_ECOLI | Aspartokinase I | Bifunctional aspartokinase/homoserine dehydrogenase 1 | thrA | thrA1 | thrA2 |
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| Type: | Protein |
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| Mol. Mass.: | 89109.15 |
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| Organism: | Escherichia coli |
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| Description: | P00561 |
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| Residue: | 820 |
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| Sequence: | MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTISGQDA
LPNISDAERIFAELLTGLAAAQPGFPLAQLKTFVDQEFAQIKHVLHGISLLGQCPDSINA
ALICRGEKMSIAIMAGVLEARGHNVTVIDPVEKLLAVGHYLESTVDIAESTRRIAASRIP
ADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTGNPQAPGTLIGASRD
EDELPVKGISNLNNMAMFSVSGPGMKGMVGMAARVFAAMSRARISVVLITQSSSEYSISF
CVPQSDCVRAERAMQEEFYLELKEGLLEPLAVTERLAIISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVNNDDATTGVRVTHQMLFNTDQVIEVFVIGVGGVGGAL
LEQLKRQQSWLKNKHIDLRVCGVANSKALLTNVHGLNLENWQEELAQAKEPFNLGRLIRL
VKEYHLLNPVIVDCTSSQAVADQYADFLREGFHVVTPNKKANTSSMDYYHQLRYAAEKSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELMKFSGILSGSLSYIFGKLDEGMSFSEATTLA
REMGYTEPDPRDDLSGMDVARKLLILARETGRELELADIEIEPVLPAEFNAEGDVAAFMA
NLSQLDDLFAARVAKARDEGKVLRYVGNIDEDGVCRVKIAEVDGNDPLFKVKNGENALAF
YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
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| BDBM92993 |
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| n/a |
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| Name | BDBM92993 |
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| Synonyms: | DL-Isoserine |
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| Type | Small molecule |
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| Emp. Form. | C3H6NO3 |
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| Mol. Mass. | 104.0852 |
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| SMILES | NCC(O)C([O-])=O |
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| Structure | 
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