| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 6 |
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| Ligand | BDBM93397 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Radioligand Binding Assay |
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| IC50 | >30±0.0 nM |
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| Citation |  Ivachtchenko, AV; Golovina, ES; Kadieva, MG; Koryakova, AG; Kovalenko, SM; Mitkin, OD; Okun, IM; Ravnyeyko, IM; Tkachenko, SE; Zaremba, OV Solution phase parallel synthesis of substituted 3-phenylsulfonyl-[1,2,3]triazolo[1,5-a]quinazolines: selective serotonin 5-HT(6) receptor antagonists. J Comb Chem12:445-52 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 6 |
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| Name: | 5-hydroxytryptamine receptor 6 |
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| Synonyms: | 5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 46968.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P50406 |
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| Residue: | 440 |
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| Sequence: | MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
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| BDBM93397 |
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| n/a |
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| Name | BDBM93397 |
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| Synonyms: | PSTQ Analog, 3{1,42} |
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| Type | Small molecule |
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| Emp. Form. | C20H22N6O2S |
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| Mol. Mass. | 410.493 |
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| SMILES | CN(C)CCN(C)c1nc2c(nnn2c2ccccc12)S(=O)(=O)c1ccccc1 |
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| Structure | 
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