Reaction Details |
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Target | Sentrin-specific protease 8 |
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Ligand | BDBM93620 |
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Substrate/Competitor | n/a |
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IC50 | 434±46 nM |
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Citation | PubChem, PC Dose-response confirmation of uHTS inhibitor hits of Sentrin-Specific Protease 8 using a kinetic assay with Nedd8 Protein Substrate PubChem Bioassay(2012)[AID] |
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More Info.: | Get all data from this article |
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Sentrin-specific protease 8 |
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Name: | Sentrin-specific protease 8 |
Synonyms: | DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 24104.52 |
Organism: | Homo sapiens (Human) |
Description: | gi_262118306 |
Residue: | 212 |
Sequence: | MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQ
FIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDS
HSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFR
QQTESLLQLLTPAYITKKRGEWKDLITTLAKK
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BDBM93620 |
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n/a |
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Name | BDBM93620 |
Synonyms: | 6-aminohexyl-(5,6-dimethoxy-8-quinolyl)amine | MLS002638313 | N'-(5,6-dimethoxy-8-quinolinyl)hexane-1,6-diamine | N'-(5,6-dimethoxyquinolin-8-yl)hexane-1,6-diamine | SMR001547800 | cid_224618 |
Type | Small organic molecule |
Emp. Form. | C17H25N3O2 |
Mol. Mass. | 303.3993 |
SMILES | COc1cc(NCCCCCCN)c2ncccc2c1OC |
Structure |
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