| Reaction Details |
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 | Report a problem with these data |
| Target | Protein Wnt-3a |
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| Ligand | BDBM36857 |
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| Substrate/Competitor | n/a |
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| IC50 | 4210±n/a nM |
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| Citation |  PubChem, PC Dose response validation of uHTS Gli-SUFU antagonist hits in a Wnt3a luminescent reporter assay PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| Protein Wnt-3a |
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| Name: | Protein Wnt-3a |
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| Synonyms: | WNT3A_MOUSE | Wnt-3a | Wnt3a | protein Wnt-3a precursor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39269.29 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_813156 |
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| Residue: | 352 |
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| Sequence: | MAPLGYLLVLCSLKQALGSYPIWWSLAVGPQYSSLSTQPILCASIPGLVPKQLRFCRNYV
EIMPSVAEGVKAGIQECQHQFRGRRWNCTTVSNSLAIFGPVLDKATRESAFVHAIASAGV
AFAVTRSCAEGSAAICGCSSRLQGSPGEGWKWGGCSEDIEFGGMVSREFADARENRPDAR
SAMNRHNNEAGRQAIASHMHLKCKCHGLSGSCEVKTCWWSQPDFRTIGDFLKDKYDSASE
MVVEKHRESRGWVETLRPRYTYFKVPTERDLVYYEASPNFCEPNPETGSFGTRDRTCNVS
SHGIDGCDLLCCGRGHNARTERRREKCHCVFHWCCYVSCQECTRVYDVHTCK
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| BDBM36857 |
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| n/a |
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| Name | BDBM36857 |
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| Synonyms: | (2,4-Dimethoxy-benzyl)-(5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)-amine | (2,4-dimethoxybenzyl)-(5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)amine | MLS000074123 | N-[(2,4-dimethoxyphenyl)methyl]-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine | SMR000007607 | cid_651526 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H17N5O2 |
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| Mol. Mass. | 299.3278 |
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| SMILES | COc1ccc(CNc2cc(C)nc3ncnn23)c(OC)c1 |
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| Structure | 
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