| Reaction Details |
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 | Report a problem with these data |
| Target | Protein Wnt-3a |
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| Ligand | BDBM89346 |
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| Substrate/Competitor | n/a |
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| IC50 | 12300±n/a nM |
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| Citation |  PubChem, PC Dose response validation of uHTS Gli-SUFU antagonist hits in a Wnt3a luminescent reporter assay PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| Protein Wnt-3a |
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| Name: | Protein Wnt-3a |
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| Synonyms: | WNT3A_MOUSE | Wnt-3a | Wnt3a | protein Wnt-3a precursor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39269.29 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_813156 |
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| Residue: | 352 |
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| Sequence: | MAPLGYLLVLCSLKQALGSYPIWWSLAVGPQYSSLSTQPILCASIPGLVPKQLRFCRNYV
EIMPSVAEGVKAGIQECQHQFRGRRWNCTTVSNSLAIFGPVLDKATRESAFVHAIASAGV
AFAVTRSCAEGSAAICGCSSRLQGSPGEGWKWGGCSEDIEFGGMVSREFADARENRPDAR
SAMNRHNNEAGRQAIASHMHLKCKCHGLSGSCEVKTCWWSQPDFRTIGDFLKDKYDSASE
MVVEKHRESRGWVETLRPRYTYFKVPTERDLVYYEASPNFCEPNPETGSFGTRDRTCNVS
SHGIDGCDLLCCGRGHNARTERRREKCHCVFHWCCYVSCQECTRVYDVHTCK
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| BDBM89346 |
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| n/a |
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| Name | BDBM89346 |
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| Synonyms: | 3-[4-(difluoromethoxy)phenyl]-1-(4-methoxyphenyl)-6,7,8,9-tetrahydro-5H-imidaz[1,2-a]azepin-4-ium;bromide | 3-[4-(difluoromethoxy)phenyl]-1-(4-methoxyphenyl)-6,7,8,9-tetrahydro-5H-imidazo[1,2-a]azepin-4-ium;bromide | 3-[4-[bis(fluoranyl)methoxy]phenyl]-1-(4-methoxyphenyl)-6,7,8,9-tetrahydro-5H-imidazo[1,2-a]azepin-4-ium;bromide | MLS001001978 | SMR000353362 | cid_16196243 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H23F2N2O2 |
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| Mol. Mass. | 385.4265 |
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| SMILES | COc1ccc(cc1)-n1cc(-c2ccc(OC(F)F)cc2)[n+]2CCCCCc12 |
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| Structure | 
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