| Reaction Details |
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 | Report a problem with these data |
| Target | Protein Wnt-3a |
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| Ligand | BDBM89352 |
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| Substrate/Competitor | n/a |
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| IC50 | 47700±n/a nM |
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| Citation |  PubChem, PC Dose response validation of uHTS Gli-SUFU antagonist hits in a Wnt3a luminescent reporter assay PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| Protein Wnt-3a |
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| Name: | Protein Wnt-3a |
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| Synonyms: | WNT3A_MOUSE | Wnt-3a | Wnt3a | protein Wnt-3a precursor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39269.29 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_813156 |
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| Residue: | 352 |
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| Sequence: | MAPLGYLLVLCSLKQALGSYPIWWSLAVGPQYSSLSTQPILCASIPGLVPKQLRFCRNYV
EIMPSVAEGVKAGIQECQHQFRGRRWNCTTVSNSLAIFGPVLDKATRESAFVHAIASAGV
AFAVTRSCAEGSAAICGCSSRLQGSPGEGWKWGGCSEDIEFGGMVSREFADARENRPDAR
SAMNRHNNEAGRQAIASHMHLKCKCHGLSGSCEVKTCWWSQPDFRTIGDFLKDKYDSASE
MVVEKHRESRGWVETLRPRYTYFKVPTERDLVYYEASPNFCEPNPETGSFGTRDRTCNVS
SHGIDGCDLLCCGRGHNARTERRREKCHCVFHWCCYVSCQECTRVYDVHTCK
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| BDBM89352 |
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| n/a |
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| Name | BDBM89352 |
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| Synonyms: | (2S,4R)-4-cyclohexyl-2-(4-hydroxybutoxy)-N-phenyl-3,4-dihydro-2H-pyran-6-carboxamide | (2S,4R)-4-cyclohexyl-2-(4-oxidanylbutoxy)-N-phenyl-3,4-dihydro-2H-pyran-6-carboxamide | MLS000766524 | SMR000441990 | cid_16197098 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H31NO4 |
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| Mol. Mass. | 373.4858 |
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| SMILES | OCCCCO[C@@H]1C[C@@H](C=C(O1)C(=O)Nc1ccccc1)C1CCCCC1 |c:9| |
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| Structure | 
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