| Reaction Details |
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 | Report a problem with these data |
| Target | Protein Wnt-3a |
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| Ligand | BDBM89414 |
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| Substrate/Competitor | n/a |
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| IC50 | 973±n/a nM |
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| Citation |  PubChem, PC Dose response validation of uHTS Gli-SUFU antagonist hits in a Wnt3a luminescent reporter assay PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| Protein Wnt-3a |
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| Name: | Protein Wnt-3a |
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| Synonyms: | WNT3A_MOUSE | Wnt-3a | Wnt3a | protein Wnt-3a precursor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39269.29 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_813156 |
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| Residue: | 352 |
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| Sequence: | MAPLGYLLVLCSLKQALGSYPIWWSLAVGPQYSSLSTQPILCASIPGLVPKQLRFCRNYV
EIMPSVAEGVKAGIQECQHQFRGRRWNCTTVSNSLAIFGPVLDKATRESAFVHAIASAGV
AFAVTRSCAEGSAAICGCSSRLQGSPGEGWKWGGCSEDIEFGGMVSREFADARENRPDAR
SAMNRHNNEAGRQAIASHMHLKCKCHGLSGSCEVKTCWWSQPDFRTIGDFLKDKYDSASE
MVVEKHRESRGWVETLRPRYTYFKVPTERDLVYYEASPNFCEPNPETGSFGTRDRTCNVS
SHGIDGCDLLCCGRGHNARTERRREKCHCVFHWCCYVSCQECTRVYDVHTCK
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| BDBM89414 |
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| n/a |
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| Name | BDBM89414 |
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| Synonyms: | MLS001111074 | N-[1-(4-tert-butylphenyl)-4,5,6,7-tetrahydroindazol-4-yl]-3-(2-ketopyrrolidino)propionamide | N-[1-(4-tert-butylphenyl)-4,5,6,7-tetrahydroindazol-4-yl]-3-(2-oxidanylidenepyrrolidin-1-yl)propanamide | N-[1-(4-tert-butylphenyl)-4,5,6,7-tetrahydroindazol-4-yl]-3-(2-oxo-1-pyrrolidinyl)propanamide | N-[1-(4-tert-butylphenyl)-4,5,6,7-tetrahydroindazol-4-yl]-3-(2-oxopyrrolidin-1-yl)propanamide | SMR000654544 | cid_24817543 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H32N4O2 |
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| Mol. Mass. | 408.5365 |
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| SMILES | CC(C)(C)c1ccc(cc1)-n1ncc2C(CCCc12)NC(=O)CCN1CCCC1=O |
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| Structure | 
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