| Reaction Details |
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 | Report a problem with these data |
| Target | Protein Wnt-3a |
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| Ligand | BDBM89485 |
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| Substrate/Competitor | n/a |
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| IC50 | >12500±n/a nM |
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| Citation |  PubChem, PC Dose response validation of uHTS Gli-SUFU antagonist hits in a Wnt3a luminescent reporter assay PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| Protein Wnt-3a |
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| Name: | Protein Wnt-3a |
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| Synonyms: | WNT3A_MOUSE | Wnt-3a | Wnt3a | protein Wnt-3a precursor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39269.29 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_813156 |
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| Residue: | 352 |
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| Sequence: | MAPLGYLLVLCSLKQALGSYPIWWSLAVGPQYSSLSTQPILCASIPGLVPKQLRFCRNYV
EIMPSVAEGVKAGIQECQHQFRGRRWNCTTVSNSLAIFGPVLDKATRESAFVHAIASAGV
AFAVTRSCAEGSAAICGCSSRLQGSPGEGWKWGGCSEDIEFGGMVSREFADARENRPDAR
SAMNRHNNEAGRQAIASHMHLKCKCHGLSGSCEVKTCWWSQPDFRTIGDFLKDKYDSASE
MVVEKHRESRGWVETLRPRYTYFKVPTERDLVYYEASPNFCEPNPETGSFGTRDRTCNVS
SHGIDGCDLLCCGRGHNARTERRREKCHCVFHWCCYVSCQECTRVYDVHTCK
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| BDBM89485 |
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| n/a |
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| Name | BDBM89485 |
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| Synonyms: | (E)-3-[4-[bis(2-bromoethyl)amino]phenyl]-2-cyano-2-propenamide | (E)-3-[4-[bis(2-bromoethyl)amino]phenyl]-2-cyano-acrylamide | (E)-3-[4-[bis(2-bromoethyl)amino]phenyl]-2-cyano-prop-2-enamide | (E)-3-[4-[bis(2-bromoethyl)amino]phenyl]-2-cyanoprop-2-enamide | MLS002701921 | SMR001565505 | cid_6282616 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H15Br2N3O |
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| Mol. Mass. | 401.096 |
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| SMILES | NC(=O)C(=C\c1ccc(cc1)N(CCBr)CCBr)\C#N |
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| Structure | 
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