| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Endothelial PAS domain-containing protein 1 |
|---|
| Ligand | BDBM65990 |
|---|
| Substrate/Competitor | n/a |
|---|
| IC50 | 8100±n/a nM |
|---|
| Citation |  PubChem, PC Dose response confirmation of uHTS identification of HIF-2a Inhibitors in a luminesence assay PubChem Bioassay(2012)[AID] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Endothelial PAS domain-containing protein 1 |
|---|
| Name: | Endothelial PAS domain-containing protein 1 |
|---|
| Synonyms: | BHLHE73 | EPAS1 | EPAS1_HUMAN | HIF2A | MOP2 | PASD2 | endothelial PAS domain-containing protein 1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 96453.58 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1506501 |
|---|
| Residue: | 870 |
|---|
| Sequence: | MTADKEKKRSSSERRKEKSRDAARCRRSKETEVFYELAHELPLPHSVSSHLDKASIMRLA
ISFLRTHKLLSSVCSENESEAEADQQMDNLYLKALEGFIAVVTQDGDMIFLSENISKFMG
LTQVELTGHSIFDFTHPCDHEEIRENLSLKNGSGFGKKSKDMSTERDFFMRMKCTVTNRG
RTVNLKSATWKVLHCTGQVKVYNNCPPHNSLCGYKEPLLSCLIIMCEPIQHPSHMDIPLD
SKTFLSRHSMDMKFTYCDDRITELIGYHPEELLGRSAYEFYHALDSENMTKSHQNLCTKG
QVVSGQYRMLAKHGGYVWLETQGTVIYNPRNLQPQCIMCVNYVLSEIEKNDVVFSMDQTE
SLFKPHLMAMNSIFDSSGKGAVSEKSNFLFTKLKEEPEELAQLAPTPGDAIISLDFGNQN
FEESSAYGKAILPPSQPWATELRSHSTQSEAGSLPAFTVPQAAAPGSTTPSATSSSSSCS
TPNSPEDYYTSLDNDLKIEVIEKLFAMDTEAKDQCSTQTDFNELDLETLAPYIPMDGEDF
QLSPICPEERLLAENPQSTPQHCFSAMTNIFQPLAPVAPHSPFLLDKFQQQLESKKTEPE
HRPMSSIFFDAGSKASLPPCCGQASTPLSSMGGRSNTQWPPDPPLHFGPTKWAVGDQRTE
FLGAAPLGPPVSPPHVSTFKTRSAKGFGARGPDVLSPAMVALSNKLKLKRQLEYEEQAFQ
DLSGGDPPGGSTSHLMWKRMKNLRGGSCPLMPDKPLSANVPNDKFTQNPMRGLGHPLRHL
PLPQPPSAISPGENSKSRFPPQCYATQYQDYSLSSAHKVSGMASRLLGPSFESYLLPELT
RYDCEVNVPVLGSSTLLQGGDLLRALDQAT
|
|
|
|---|
| BDBM65990 |
|---|
| n/a |
|---|
| Name | BDBM65990 |
|---|
| Synonyms: | 3-[2,5-bis(oxidanylidene)pyrrol-1-yl]-N-(2,4-dichlorophenyl)benzamide | MLS000572761 | N-(2,4-dichlorophenyl)-3-(2,5-dioxo-1-pyrrolyl)benzamide | N-(2,4-dichlorophenyl)-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzamide | N-(2,4-dichlorophenyl)-3-(2,5-dioxopyrrol-1-yl)benzamide | N-(2,4-dichlorophenyl)-3-maleimido-benzamide | SMR000194626 | cid_2275069 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H10Cl2N2O3 |
|---|
| Mol. Mass. | 361.179 |
|---|
| SMILES | Clc1ccc(NC(=O)c2cccc(c2)N2C(=O)C=CC2=O)c(Cl)c1 |c:18| |
|---|
| Structure | 
|
|---|
Search and Browse
