| Reaction Details |
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 | Report a problem with these data |
| Target | Corticotropin-releasing factor-binding protein |
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| Ligand | BDBM89733 |
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| Substrate/Competitor | n/a |
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| IC50 | 3480±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS hits for small molecule antagonists of the CRF-binding protein and CRF-R2 receptor complex in 384 well format PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| Corticotropin-releasing factor-binding protein |
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| Name: | Corticotropin-releasing factor-binding protein |
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| Synonyms: | CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36143.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P24387 |
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| Residue: | 322 |
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| Sequence: | MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRC
LDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKG
EKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNL
FPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGI
GDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQ
LEPYELENPNGNSIGEFCLSGL
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| BDBM89733 |
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| n/a |
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| Name | BDBM89733 |
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| Synonyms: | 1-(2,5-dimethoxyphenyl)sulfonyl-2-methyl-2,3-dihydroindole | 1-(2,5-dimethoxyphenyl)sulfonyl-2-methyl-indoline | 1-[(2,5-dimethoxyphenyl)sulfonyl]-2-methylindoline | MLS000096610 | SMR000073745 | cid_2943266 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H19NO4S |
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| Mol. Mass. | 333.402 |
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| SMILES | COc1ccc(OC)c(c1)S(=O)(=O)N1C(C)Cc2ccccc12 |
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| Structure | 
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