| Reaction Details |
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 | Report a problem with these data |
| Target | Corticotropin-releasing factor-binding protein |
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| Ligand | BDBM89544 |
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| Substrate/Competitor | n/a |
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| IC50 | 3720±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS hits for small molecule antagonists of the CRF-binding protein and CRF-R2 receptor complex in 384 well format PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| Corticotropin-releasing factor-binding protein |
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| Name: | Corticotropin-releasing factor-binding protein |
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| Synonyms: | CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36143.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P24387 |
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| Residue: | 322 |
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| Sequence: | MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRC
LDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKG
EKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNL
FPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGI
GDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQ
LEPYELENPNGNSIGEFCLSGL
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| BDBM89544 |
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| n/a |
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| Name | BDBM89544 |
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| Synonyms: | (2,4-Dimethoxy-phenyl)-[6-(2-fluoro-phenyl)-pyridazin-3-yl]-amine | (2,4-dimethoxyphenyl)-[6-(2-fluorophenyl)pyridazin-3-yl]amine | MLS000075679 | N-(2,4-dimethoxyphenyl)-6-(2-fluorophenyl)-3-pyridazinamine | N-(2,4-dimethoxyphenyl)-6-(2-fluorophenyl)pyridazin-3-amine | SMR000007238 | cid_653238 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H16FN3O2 |
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| Mol. Mass. | 325.3369 |
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| SMILES | COc1ccc(Nc2ccc(nn2)-c2ccccc2F)c(OC)c1 |
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| Structure | 
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