Reaction Details |
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Target | Corticotropin-releasing factor-binding protein |
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Ligand | BDBM51126 |
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Substrate/Competitor | n/a |
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IC50 | 1460±n/a nM |
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Citation | PubChem, PC Dose Response confirmation of uHTS hits for small molecule antagonists of the CRF-binding protein and CRF-R2 receptor complex in 384 well format PubChem Bioassay(2012)[AID] |
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More Info.: | Get all data from this article |
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Corticotropin-releasing factor-binding protein |
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Name: | Corticotropin-releasing factor-binding protein |
Synonyms: | CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 36143.95 |
Organism: | Homo sapiens (Human) |
Description: | P24387 |
Residue: | 322 |
Sequence: | MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRC
LDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKG
EKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNL
FPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGI
GDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQ
LEPYELENPNGNSIGEFCLSGL
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BDBM51126 |
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n/a |
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Name | BDBM51126 |
Synonyms: | 2-(3,4,5-trimethoxybenzylidene)indane-1,3-quinone | 2-[(3,4,5-trimethoxyphenyl)methylidene]indene-1,3-dione | MLS000718012 | SMR000279580 | cid_827945 |
Type | Small organic molecule |
Emp. Form. | C19H16O5 |
Mol. Mass. | 324.3273 |
SMILES | [#6]-[#8]-c1cc(\[#6]=[#6]-2/[#6](=O)-c3ccccc3-[#6]-2=O)cc(-[#8]-[#6])c1-[#8]-[#6] |
Structure |
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