| Reaction Details |
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 | Report a problem with these data |
| Target | Corticotropin-releasing factor-binding protein |
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| Ligand | BDBM78182 |
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| Substrate/Competitor | n/a |
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| IC50 | 5100±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS hits for small molecule antagonists of the CRF-binding protein and CRF-R2 receptor complex in 384 well format PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| Corticotropin-releasing factor-binding protein |
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| Name: | Corticotropin-releasing factor-binding protein |
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| Synonyms: | CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36143.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P24387 |
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| Residue: | 322 |
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| Sequence: | MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRC
LDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKG
EKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNL
FPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGI
GDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQ
LEPYELENPNGNSIGEFCLSGL
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| BDBM78182 |
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| n/a |
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| Name | BDBM78182 |
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| Synonyms: | 2-(3,4-dichlorophenyl)-N'-[(3,4-dimethoxybenzoyl)oxy]ethanimidamide | 3,4-dimethoxybenzoic acid [(Z)-[1-amino-2-(3,4-dichlorophenyl)ethylidene]amino] ester | MLS000578928 | SMR000198749 | [(Z)-[1-amino-2-(3,4-dichlorophenyl)ethylidene]amino] 3,4-dimethoxybenzoate | [(Z)-[1-azanyl-2-(3,4-dichlorophenyl)ethylidene]amino] 3,4-dimethoxybenzoate | cid_9587530 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H16Cl2N2O4 |
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| Mol. Mass. | 383.226 |
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| SMILES | COc1ccc(cc1OC)C(=O)ON=C(N)Cc1ccc(Cl)c(Cl)c1 |w:13.13| |
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| Structure | 
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