| Reaction Details |
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 | Report a problem with these data |
| Target | Xylosyl- and glucuronyltransferase LARGE1 |
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| Ligand | BDBM94709 |
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| Substrate/Competitor | n/a |
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| EC50 | 5600±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation of small molecule activators of alpha dystroglycan glycosylation PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| Xylosyl- and glucuronyltransferase LARGE1 |
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| Name: | Xylosyl- and glucuronyltransferase LARGE1 |
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| Synonyms: | KIAA0609 | LARG1_HUMAN | LARGE | LARGE1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 88079.63 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_47678551 |
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| Residue: | 756 |
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| Sequence: | MLGICRGRRKFLAASLSLLCIPAITWIYLFSGSFEDGKPVSLSPLESQAHSPRYTASSQR
ERESLEVRMREVEEENRALRRQLSLAQGRAPSHRRGNHSKTYSMEEGTGDSENLRAGIVA
GNSSECGQQPVVEKCETIHVAIVCAGYNASRDVVTLVKSVLFHRRNPLHFHLIADSIAEQ
ILATLFQTWMVPAVRVDFYNADELKSEVSWIPNKHYSGIYGLMKLVLTKTLPANLERVIV
LDTDITFATDIAELWAVFHKFKGQQVLGLVENQSDWYLGNLWKNHRPWPALGRGYNTGVI
LLLLDKLRKMKWEQMWRLTAERELMGMLSTSLADQDIFNAVIKQNPFLVYQLPCFWNVQL
SDHTRSEQCYRDVSDLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELFGCP
SEADVNSENLQKQLSELDEDDLCYEFRRERFTVHRTHLYFLHYEYEPAADSTDVTLVAQL
SMDRLQMLEAICKHWEGPISLALYLSDAEAQQFLRYAQGSEVLMSRHNVGYHIVYKEGQF
YPVNLLRNVAMKHISTPYMFLSDIDFLPMYGLYEYLRKSVIQLDLANTKKAMIVPAFETL
RYRLSFPKSKAELLSMLDMGTLFTFRYHVWTKGHAPTNFAKWRTATTPYRVEWEADFEPY
VVVRRDCPEYDRRFVGFGWNKVAHIMELDVQEYEFIVLPNAYMIHMPHAPSFDITKFRSN
KQYRICLKTLKEEFQQDMSRRYGFAALKYLTAENNS
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| BDBM94709 |
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| n/a |
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| Name | BDBM94709 |
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| Synonyms: | 4-(azepan-1-ylcarbonyl)-2-(4-ethoxyphenyl)-6,7-dimethoxy-isoquinolin-1-one | 4-(azepan-1-ylcarbonyl)-2-(4-ethoxyphenyl)-6,7-dimethoxyisoquinolin-1(2H)-one | 4-(azepane-1-carbonyl)-2-(4-ethoxyphenyl)-6,7-dimethoxyisoquinolin-1-one | 4-(azepane-1-carbonyl)-6,7-dimethoxy-2-p-phenetyl-isocarbostyril | 4-[1-azepanyl(oxo)methyl]-2-(4-ethoxyphenyl)-6,7-dimethoxy-1-isoquinolinone | MLS000086366 | SMR000021868 | cid_3237252 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H30N2O5 |
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| Mol. Mass. | 450.5268 |
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| SMILES | CCOc1ccc(cc1)-n1cc(C(=O)N2CCCCCC2)c2cc(OC)c(OC)cc2c1=O |
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| Structure | 
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