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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Xylosyl- and glucuronyltransferase LARGE1 | ||
| Ligand | BDBM94733 | ||
| Substrate/Competitor | n/a | ||
| EC50 | 1900±n/a nM | ||
| Citation |  PubChem, PC Dose response confirmation of small molecule activators of alpha dystroglycan glycosylation PubChem Bioassay(2012)[AID] | ||
| More Info.: | Get all data from this article | ||
| Xylosyl- and glucuronyltransferase LARGE1 | |||
| Name: | Xylosyl- and glucuronyltransferase LARGE1 | ||
| Synonyms: | KIAA0609 | LARG1_HUMAN | LARGE | LARGE1 | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 88079.63 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | gi_47678551 | ||
| Residue: | 756 | ||
| Sequence: |
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| BDBM94733 | |||
| n/a | |||
| Name | BDBM94733 | ||
| Synonyms: | MLS001061376 | N-[2-(dimethylamino)-2-(4-ethylphenyl)ethyl]-3-(2-fluorophenyl)-4-keto-2-thioxo-1H-quinazoline-7-carboxamide | N-[2-(dimethylamino)-2-(4-ethylphenyl)ethyl]-3-(2-fluorophenyl)-4-oxidanylidene-2-sulfanylidene-1H-quinazoline-7-carboxamide | N-[2-(dimethylamino)-2-(4-ethylphenyl)ethyl]-3-(2-fluorophenyl)-4-oxo-2-sulfanylidene-1H-quinazoline-7-carboxamide | SMR000384994 | cid_4969557 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H27FN4O2S | ||
| Mol. Mass. | 490.592 | ||
| SMILES | CCc1ccc(cc1)C(CNC(=O)c1ccc2c(c1)[nH]c(=S)n(-c1ccccc1F)c2=O)N(C)C |(24.51,-3.12,;23.18,-3.89,;21.85,-3.11,;20.51,-3.88,;19.18,-3.1,;19.19,-1.56,;20.52,-.8,;21.85,-1.57,;17.86,-.79,;16.52,-1.55,;15.19,-.78,;13.85,-1.54,;13.85,-3.08,;12.52,-.77,;12.52,.84,;11.13,1.63,;9.75,.81,;9.75,-.73,;11.13,-1.56,;8.41,-1.5,;7.08,-.73,;5.75,-1.5,;7.08,.81,;5.75,1.58,;4.41,.81,;3.08,1.58,;3.08,3.12,;4.41,3.89,;5.75,3.12,;7.08,3.89,;8.41,1.58,;8.41,3.12,;17.86,.75,;19.2,1.52,;16.53,1.53,)| | ||
| Structure | 
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