| Reaction Details |
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 | Report a problem with these data |
| Target | Xylosyl- and glucuronyltransferase LARGE1 |
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| Ligand | BDBM64392 |
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| Substrate/Competitor | n/a |
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| EC50 | 8890±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation of small molecule activators of alpha dystroglycan glycosylation PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| Xylosyl- and glucuronyltransferase LARGE1 |
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| Name: | Xylosyl- and glucuronyltransferase LARGE1 |
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| Synonyms: | KIAA0609 | LARG1_HUMAN | LARGE | LARGE1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 88079.63 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_47678551 |
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| Residue: | 756 |
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| Sequence: | MLGICRGRRKFLAASLSLLCIPAITWIYLFSGSFEDGKPVSLSPLESQAHSPRYTASSQR
ERESLEVRMREVEEENRALRRQLSLAQGRAPSHRRGNHSKTYSMEEGTGDSENLRAGIVA
GNSSECGQQPVVEKCETIHVAIVCAGYNASRDVVTLVKSVLFHRRNPLHFHLIADSIAEQ
ILATLFQTWMVPAVRVDFYNADELKSEVSWIPNKHYSGIYGLMKLVLTKTLPANLERVIV
LDTDITFATDIAELWAVFHKFKGQQVLGLVENQSDWYLGNLWKNHRPWPALGRGYNTGVI
LLLLDKLRKMKWEQMWRLTAERELMGMLSTSLADQDIFNAVIKQNPFLVYQLPCFWNVQL
SDHTRSEQCYRDVSDLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELFGCP
SEADVNSENLQKQLSELDEDDLCYEFRRERFTVHRTHLYFLHYEYEPAADSTDVTLVAQL
SMDRLQMLEAICKHWEGPISLALYLSDAEAQQFLRYAQGSEVLMSRHNVGYHIVYKEGQF
YPVNLLRNVAMKHISTPYMFLSDIDFLPMYGLYEYLRKSVIQLDLANTKKAMIVPAFETL
RYRLSFPKSKAELLSMLDMGTLFTFRYHVWTKGHAPTNFAKWRTATTPYRVEWEADFEPY
VVVRRDCPEYDRRFVGFGWNKVAHIMELDVQEYEFIVLPNAYMIHMPHAPSFDITKFRSN
KQYRICLKTLKEEFQQDMSRRYGFAALKYLTAENNS
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| BDBM64392 |
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| n/a |
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| Name | BDBM64392 |
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| Synonyms: | 1-(4-methoxy-2,3-dimethyl-benzyl)-N-[4-(3-pyridyloxy)phenyl]isonipecotamide | 1-[(4-methoxy-2,3-dimethyl-phenyl)methyl]-N-(4-pyridin-3-yloxyphenyl)piperidine-4-carboxamide | 1-[(4-methoxy-2,3-dimethylphenyl)methyl]-N-(4-pyridin-3-yloxyphenyl)piperidine-4-carboxamide | 1-[(4-methoxy-2,3-dimethylphenyl)methyl]-N-[4-(3-pyridinyloxy)phenyl]-4-piperidinecarboxamide | MLS001090782 | SMR000653599 | cid_24817212 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H31N3O3 |
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| Mol. Mass. | 445.5533 |
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| SMILES | COc1ccc(CN2CCC(CC2)C(=O)Nc2ccc(Oc3cccnc3)cc2)c(C)c1C |
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| Structure | 
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