| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Xylosyl- and glucuronyltransferase LARGE1 |
|---|
| Ligand | BDBM94762 |
|---|
| Substrate/Competitor | n/a |
|---|
| EC50 | 8930±n/a nM |
|---|
| Citation |  PubChem, PC Dose response confirmation of small molecule activators of alpha dystroglycan glycosylation PubChem Bioassay(2012)[AID] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Xylosyl- and glucuronyltransferase LARGE1 |
|---|
| Name: | Xylosyl- and glucuronyltransferase LARGE1 |
|---|
| Synonyms: | KIAA0609 | LARG1_HUMAN | LARGE | LARGE1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 88079.63 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_47678551 |
|---|
| Residue: | 756 |
|---|
| Sequence: | MLGICRGRRKFLAASLSLLCIPAITWIYLFSGSFEDGKPVSLSPLESQAHSPRYTASSQR
ERESLEVRMREVEEENRALRRQLSLAQGRAPSHRRGNHSKTYSMEEGTGDSENLRAGIVA
GNSSECGQQPVVEKCETIHVAIVCAGYNASRDVVTLVKSVLFHRRNPLHFHLIADSIAEQ
ILATLFQTWMVPAVRVDFYNADELKSEVSWIPNKHYSGIYGLMKLVLTKTLPANLERVIV
LDTDITFATDIAELWAVFHKFKGQQVLGLVENQSDWYLGNLWKNHRPWPALGRGYNTGVI
LLLLDKLRKMKWEQMWRLTAERELMGMLSTSLADQDIFNAVIKQNPFLVYQLPCFWNVQL
SDHTRSEQCYRDVSDLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELFGCP
SEADVNSENLQKQLSELDEDDLCYEFRRERFTVHRTHLYFLHYEYEPAADSTDVTLVAQL
SMDRLQMLEAICKHWEGPISLALYLSDAEAQQFLRYAQGSEVLMSRHNVGYHIVYKEGQF
YPVNLLRNVAMKHISTPYMFLSDIDFLPMYGLYEYLRKSVIQLDLANTKKAMIVPAFETL
RYRLSFPKSKAELLSMLDMGTLFTFRYHVWTKGHAPTNFAKWRTATTPYRVEWEADFEPY
VVVRRDCPEYDRRFVGFGWNKVAHIMELDVQEYEFIVLPNAYMIHMPHAPSFDITKFRSN
KQYRICLKTLKEEFQQDMSRRYGFAALKYLTAENNS
|
|
|
|---|
| BDBM94762 |
|---|
| n/a |
|---|
| Name | BDBM94762 |
|---|
| Synonyms: | 4-[1-amino-2-(4-chlorophenyl)ethyl]-N-(4-methylsulfonylphenyl)-1,3-thiazol-2-amine | 4-[1-amino-2-(4-chlorophenyl)ethyl]-N-(4-methylsulfonylphenyl)-2-thiazolamine | 4-[1-azanyl-2-(4-chlorophenyl)ethyl]-N-(4-methylsulfonylphenyl)-1,3-thiazol-2-amine | MLS003123770 | SMR001291831 | [4-[1-amino-2-(4-chlorophenyl)ethyl]thiazol-2-yl]-(4-mesylphenyl)amine | cid_46942717 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H18ClN3O2S2 |
|---|
| Mol. Mass. | 407.937 |
|---|
| SMILES | CS(=O)(=O)c1ccc(Nc2nc(cs2)C(N)Cc2ccc(Cl)cc2)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
