| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sentrin-specific protease 1 |
|---|
| Ligand | BDBM41873 |
|---|
| Substrate/Competitor | n/a |
|---|
| IC50 | 15000±n/a nM |
|---|
| Citation |  PubChem, PC Dose response confirmation of small molecule inhibitors of the catalytic domain of the SUMO protease, SENP1 in a kinetic FRET assay PubChem Bioassay(2012)[AID] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Sentrin-specific protease 1 |
|---|
| Name: | Sentrin-specific protease 1 |
|---|
| Synonyms: | SENP1 | SENP1_HUMAN | Sentrin-specific protease 1 (SENP1) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 73500.42 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q9P0U3 |
|---|
| Residue: | 644 |
|---|
| Sequence: | MDDIADRMRMDAGEVTLVNHNSVFKTHLLPQTGFPEDQLSLSDQQILSSRQGHLDRSFTC
STRSAAYNPSYYSDNPSSDSFLGSGDLRTFGQSANGQWRNSTPSSSSSLQKSRNSRSLYL
ETRKTSSGLSNSFAGKSNHHCHVSAYEKSFPIKPVPSPSWSGSCRRSLLSPKKTQRRHVS
TAEETVQEEEREIYRQLLQMVTGKQFTIAKPTTHFPLHLSRCLSSSKNTLKDSLFKNGNS
CASQIIGSDTSSSGSASILTNQEQLSHSVYSLSSYTPDVAFGSKDSGTLHHPHHHHSVPH
QPDNLAASNTQSEGSDSVILLKVKDSQTPTPSSTFFQAELWIKELTSVYDSRARERLRQI
EEQKALALQLQNQRLQEREHSVHDSVELHLRVPLEKEIPVTVVQETQKKGHKLTDSEDEF
PEITEEMEKEIKNVFRNGNQDEVLSEAFRLTITRKDIQTLNHLNWLNDEIINFYMNMLME
RSKEKGLPSVHAFNTFFFTKLKTAGYQAVKRWTKKVDVFSVDILLVPIHLGVHWCLAVVD
FRKKNITYYDSMGGINNEACRILLQYLKQESIDKKRKEFDTNGWQLFSKKSQEIPQQMNG
SDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILHRKLL
|
|
|
|---|
| BDBM41873 |
|---|
| n/a |
|---|
| Name | BDBM41873 |
|---|
| Synonyms: | 2-[5-(2-furanyl)-1H-1,2,4-triazol-3-yl]-1,3-dioxo-5-isoindolecarboxylic acid | 2-[5-(2-furyl)-1H-1,2,4-triazol-3-yl]-1,3-diketo-isoindoline-5-carboxylic acid | 2-[5-(furan-2-yl)-1H-1,2,4-triazol-3-yl]-1,3-bis(oxidanylidene)isoindole-5-carboxylic acid | 2-[5-(furan-2-yl)-1H-1,2,4-triazol-3-yl]-1,3-dioxoisoindole-5-carboxylic acid | MLS-0146260.0001 | cid_2971779 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H8N4O5 |
|---|
| Mol. Mass. | 324.2478 |
|---|
| SMILES | OC(=O)c1ccc2C(=O)N(C(=O)c2c1)c1nnc([nH]1)-c1ccco1 |
|---|
| Structure | 
|
|---|
Search and Browse
